Jay Wright — Record When Ranked AP Top 5
130–26
83.3%
win rate
+12.3
avg margin
156
games
Games (156)
| # | Date | Season | School | Opponent | Opp. Conf. | Loc | W/L | Score | Type | Arena |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2005-11-18 | 2005–06 | #5 Villanova | Stony Brook | Am. East | Home | W | 78–35 | Regular | Xfinity Mobile Arena |
| 2 | 2005-11-27 | 2005–06 | #4 Villanova | Lehigh | Patriot | Home | W | 84–47 | Regular | Xfinity Mobile Arena |
| 3 | 2005-11-30 | 2005–06 | #4 Villanova | Rider | MAAC | Home | W | 86–57 | Regular | Xfinity Mobile Arena |
| 4 | 2005-12-03 | 2005–06 | #4 Villanova | #5 Oklahoma | B12 | Home | W | 85–74 | Regular | Xfinity Mobile Arena |
| 5 | 2005-12-06 | 2005–06 | #4 Villanova | Bucknell | Patriot | Away | W | 79–60 | Regular | Sojka Pavilion |
| 6 | 2005-12-10 | 2005–06 | #4 Villanova | Longwood | Independent | Neutral | W | 90–77 | Regular | Boardwalk Hall |
| 7 | 2005-12-13 | 2005–06 | #3 Villanova | Pennsylvania | Ivy | Away | W | 62–55 | Regular | The Palestra |
| 8 | 2005-12-22 | 2005–06 | #3 Villanova | La Salle | A10 | Home | W | 98–57 | Regular | Xfinity Mobile Arena |
| 9 | 2005-12-31 | 2005–06 | #3 Villanova | Temple | A10 | Neutral | W | 75–53 | Regular | The Palestra |
| 10 | 2006-01-05 | 2005–06 | #3 Villanova | #9 Louisville | Big East | Away | W | 76–67 | Regular | Freedom Hall |
| 11 | 2006-01-08 | 2005–06 | #3 Villanova | #24 West Virginia | Big East | Home | L | 87–91 | Regular | Finneran Pavilion |
| 12 | 2006-01-11 | 2005–06 | #3 Villanova | Rutgers | Big East | Away | W | 84–78 OT | Regular | Jersey Mike's Arena |
| 13 | 2006-01-14 | 2005–06 | #3 Villanova | #8 Texas | B12 | Away | L | 55–58 | Regular | Frank Erwin Center |
| 14 | 2006-01-30 | 2005–06 | #4 Villanova | Louisville | Big East | Home | W | 79–73 | Regular | Xfinity Mobile Arena |
| 15 | 2006-02-04 | 2005–06 | #4 Villanova | Marquette | Big East | Home | W | 72–67 | Regular | Xfinity Mobile Arena |
| 16 | 2006-02-07 | 2005–06 | #4 Villanova | Saint Joseph's | A10 | Neutral | W | 71–58 | Regular | The Palestra |
| 17 | 2006-02-11 | 2005–06 | #4 Villanova | DePaul | Big East | Away | W | 61–51 | Regular | Allstate Arena |
| 18 | 2006-02-13 | 2005–06 | #4 Villanova | #1 Connecticut | Big East | Home | W | 69–64 | Regular | Xfinity Mobile Arena |
| 19 | 2006-02-19 | 2005–06 | #4 Villanova | #17 Georgetown | Big East | Home | W | 75–65 | Regular | Xfinity Mobile Arena |
| 20 | 2006-02-23 | 2005–06 | #2 Villanova | Cincinnati | Big East | Away | W | 74–72 | Regular | Fifth Third Arena |
| 21 | 2006-02-26 | 2005–06 | #2 Villanova | #3 Connecticut | Big East | Away | L | 75–89 | Regular | Harry A. Gampel Pavilion |
| 22 | 2006-03-01 | 2005–06 | #4 Villanova | St. John's (NY) | Big East | Home | W | 65–52 | Regular | Xfinity Mobile Arena |
| 23 | 2006-03-05 | 2005–06 | #4 Villanova | Syracuse | Big East | Away | W | 92–82 | Regular | Carrier Dome |
| 24 | 2006-03-09 | 2005–06 | #2 Villanova | Rutgers | Big East | Neutral | W | 87–55 | Conf. Tourn. | Madison Square Garden |
| 25 | 2006-03-10 | 2005–06 | #2 Villanova | #15 Pittsburgh | Big East | Neutral | L | 54–68 | Conf. Tourn. | Madison Square Garden |
| 26 | 2009-11-13 | 2009–10 | #5 Villanova | FDU | NEC | Home | W | 84–61 | Regular | Xfinity Mobile Arena |
| 27 | 2009-11-16 | 2009–10 | #5 Villanova | Pennsylvania | Ivy | Home | W | 103–65 | Regular | Xfinity Mobile Arena |
| 28 | 2009-11-19 | 2009–10 | #5 Villanova | George Mason | Colonial | Neutral | W | 69–68 | Regular | José Miguel Agrelot Coliseum |
| 29 | 2009-11-20 | 2009–10 | #5 Villanova | #18 Dayton | A10 | Neutral | W | 71–65 | Regular | José Miguel Agrelot Coliseum |
| 30 | 2009-11-22 | 2009–10 | #5 Villanova | Mississippi | SEC | Neutral | W | 79–67 | Regular | José Miguel Agrelot Coliseum |
| 31 | 2009-11-28 | 2009–10 | #4 Villanova | La Salle | A10 | Home | W | 81–63 | Regular | Xfinity Mobile Arena |
| 32 | 2009-12-02 | 2009–10 | #3 Villanova | Drexel | Colonial | Home | W | 77–58 | Regular | Xfinity Mobile Arena |
| 33 | 2009-12-06 | 2009–10 | #3 Villanova | Maryland | ACC | Neutral | W | 95–86 | Regular | Capital One Arena |
| 34 | 2009-12-09 | 2009–10 | #3 Villanova | Saint Joseph's | A10 | Neutral | W | 97–89 | Regular | The Palestra |
| 35 | 2009-12-13 | 2009–10 | #3 Villanova | Temple | A10 | Away | L | 65–75 | Regular | Liacouras Center |
| 36 | 2010-01-11 | 2009–10 | #4 Villanova | Louisville | Big East | Away | W | 92–84 | Regular | Freedom Hall |
| 37 | 2010-01-17 | 2009–10 | #4 Villanova | #11 Georgetown | Big East | Home | W | 82–77 | Regular | Xfinity Mobile Arena |
| 38 | 2010-01-20 | 2009–10 | #4 Villanova | Rutgers | Big East | Away | W | 94–68 | Regular | Jersey Mike's Arena |
| 39 | 2010-01-23 | 2009–10 | #4 Villanova | St. John's (NY) | Big East | Away | W | 81–71 | Regular | Madison Square Garden |
| 40 | 2010-01-27 | 2009–10 | #3 Villanova | Notre Dame | Big East | Home | W | 90–72 | Regular | Xfinity Mobile Arena |
| 41 | 2010-02-02 | 2009–10 | #2 Villanova | Seton Hall | Big East | Home | W | 81–71 | Regular | Xfinity Mobile Arena |
| 42 | 2010-02-06 | 2009–10 | #2 Villanova | #7 Georgetown | Big East | Away | L | 90–103 | Regular | Capital One Arena |
| 43 | 2010-02-08 | 2009–10 | #4 Villanova | #5 West Virginia | Big East | Away | W | 82–75 | Regular | Hope Coliseum |
| 44 | 2010-02-13 | 2009–10 | #4 Villanova | Providence | Big East | Home | W | 92–81 | Regular | Xfinity Mobile Arena |
| 45 | 2010-02-15 | 2009–10 | #3 Villanova | Connecticut | Big East | Home | L | 75–84 | Regular | Xfinity Mobile Arena |
| 46 | 2010-02-21 | 2009–10 | #3 Villanova | #19 Pittsburgh | Big East | Away | L | 65–70 | Regular | Petersen Events Center |
| 47 | 2014-01-20 | 2013–14 | #4 Villanova | Creighton | Big East | Home | L | 68–96 | Regular | Xfinity Mobile Arena |
| 48 | 2014-01-25 | 2013–14 | #4 Villanova | Marquette | Big East | Away | W | 94–85 OT | Regular | Bradley Center |
| 49 | 2014-03-13 | 2013–14 | #3 Villanova | Seton Hall | Big East | Neutral | L | 63–64 | Conf. Tourn. | Madison Square Garden |
| 50 | 2015-01-14 | 2014–15 | #5 Villanova | Xavier | Big East | Home | W | 88–75 | Regular | Finneran Pavilion |
| 51 | 2015-01-17 | 2014–15 | #5 Villanova | Pennsylvania | Ivy | Away | W | 62–47 | Regular | The Palestra |
| 52 | 2015-01-19 | 2014–15 | #4 Villanova | Georgetown | Big East | Away | L | 58–78 | Regular | Capital One Arena |
| 53 | 2015-01-25 | 2014–15 | #4 Villanova | Creighton | Big East | Home | W | 71–50 | Regular | Finneran Pavilion |
| 54 | 2015-03-03 | 2014–15 | #4 Villanova | Creighton | Big East | Away | W | 76–72 | Regular | CHI Health Center Omaha |
| 55 | 2015-03-07 | 2014–15 | #4 Villanova | St. John's (NY) | Big East | Home | W | 105–68 | Regular | Xfinity Mobile Arena |
| 56 | 2015-03-12 | 2014–15 | #4 Villanova | Marquette | Big East | Neutral | W | 84–49 | Conf. Tourn. | Madison Square Garden |
| 57 | 2015-03-13 | 2014–15 | #4 Villanova | Providence | Big East | Neutral | W | 63–61 | Conf. Tourn. | Madison Square Garden |
| 58 | 2015-03-14 | 2014–15 | #4 Villanova | Xavier | Big East | Neutral | W | 69–52 | Conf. Tourn. | Madison Square Garden |
| 59 | 2016-01-20 | 2015–16 | #4 Villanova | Seton Hall | Big East | Away | W | 72–71 | Regular | Prudential Center |
| 60 | 2016-01-24 | 2015–16 | #4 Villanova | #16 Providence | Big East | Home | L | 76–82 OT | Regular | Xfinity Mobile Arena |
| 61 | 2016-02-03 | 2015–16 | #3 Villanova | Creighton | Big East | Home | W | 83–58 | Regular | Finneran Pavilion |
| 62 | 2016-02-06 | 2015–16 | #3 Villanova | #11 Providence | Big East | Away | W | 72–60 | Regular | Amica Mutual Pavilion |
| 63 | 2016-02-09 | 2015–16 | #1 Villanova | DePaul | Big East | Away | W | 86–59 | Regular | Allstate Arena |
| 64 | 2016-02-13 | 2015–16 | #1 Villanova | St. John's (NY) | Big East | Home | W | 73–63 | Regular | Xfinity Mobile Arena |
| 65 | 2016-02-17 | 2015–16 | #1 Villanova | Temple | AAC | Away | W | 83–67 | Regular | Liacouras Center |
| 66 | 2016-02-20 | 2015–16 | #1 Villanova | Butler | Big East | Home | W | 77–67 | Regular | Finneran Pavilion |
| 67 | 2016-02-24 | 2015–16 | #1 Villanova | #5 Xavier | Big East | Away | L | 83–90 | Regular | Cintas Center |
| 68 | 2016-02-27 | 2015–16 | #1 Villanova | Marquette | Big East | Away | W | 89–79 | Regular | Bradley Center |
| 69 | 2016-03-01 | 2015–16 | #3 Villanova | DePaul | Big East | Home | W | 83–62 | Regular | Finneran Pavilion |
| 70 | 2016-03-05 | 2015–16 | #3 Villanova | Georgetown | Big East | Home | W | 84–71 | Regular | Finneran Pavilion |
| 71 | 2016-03-10 | 2015–16 | #3 Villanova | Georgetown | Big East | Neutral | W | 81–67 | Conf. Tourn. | Madison Square Garden |
| 72 | 2016-03-11 | 2015–16 | #3 Villanova | Providence | Big East | Neutral | W | 76–68 | Conf. Tourn. | Madison Square Garden |
| 73 | 2016-03-12 | 2015–16 | #3 Villanova | Seton Hall | Big East | Neutral | L | 67–69 | Conf. Tourn. | Madison Square Garden |
| 74 | 2016-11-11 | 2016–17 | #4 Villanova | Lafayette | Patriot | Home | W | 88–48 | Regular | Finneran Pavilion |
| 75 | 2016-11-14 | 2016–17 | #3 Villanova | #15 Purdue | B10 | Away | W | 79–76 | Regular | Mackey Arena |
| 76 | 2016-11-17 | 2016–17 | #3 Villanova | Western Michigan | MAC | Neutral | W | 76–65 | Regular | TD Arena |
| 77 | 2016-11-18 | 2016–17 | #3 Villanova | Wake Forest | ACC | Neutral | W | 96–77 | Regular | TD Arena |
| 78 | 2016-11-20 | 2016–17 | #3 Villanova | UCF | AAC | Neutral | W | 67–57 | Regular | TD Arena |
| 79 | 2016-11-23 | 2016–17 | #2 Villanova | College of Charleston | Colonial | Home | W | 63–47 | Regular | Finneran Pavilion |
| 80 | 2016-11-29 | 2016–17 | #2 Villanova | Pennsylvania | Ivy | Away | W | 82–57 | Regular | The Palestra |
| 81 | 2016-12-03 | 2016–17 | #2 Villanova | Saint Joseph's | A10 | Home | W | 88–57 | Regular | Finneran Pavilion |
| 82 | 2016-12-06 | 2016–17 | #1 Villanova | La Salle | A10 | Neutral | W | 89–79 | Regular | The Palestra |
| 83 | 2016-12-10 | 2016–17 | #1 Villanova | #23 Notre Dame | ACC | Neutral | W | 74–66 | Regular | Prudential Center |
| 84 | 2016-12-13 | 2016–17 | #1 Villanova | Temple | AAC | Home | W | 78–57 | Regular | Finneran Pavilion |
| 85 | 2016-12-21 | 2016–17 | #1 Villanova | American | Patriot | Home | W | 90–48 | Regular | Finneran Pavilion |
| 86 | 2016-12-28 | 2016–17 | #1 Villanova | DePaul | Big East | Home | W | 68–65 | Regular | Finneran Pavilion |
| 87 | 2016-12-31 | 2016–17 | #1 Villanova | #10 Creighton | Big East | Away | W | 80–70 | Regular | CHI Health Center Omaha |
| 88 | 2017-01-04 | 2016–17 | #1 Villanova | #18 Butler | Big East | Away | L | 58–66 | Regular | Hinkle Fieldhouse |
| 89 | 2017-01-07 | 2016–17 | #1 Villanova | Marquette | Big East | Home | W | 93–81 | Regular | Xfinity Mobile Arena |
| 90 | 2017-01-10 | 2016–17 | #3 Villanova | #15 Xavier | Big East | Home | W | 79–54 | Regular | Finneran Pavilion |
| 91 | 2017-01-14 | 2016–17 | #3 Villanova | St. John's (NY) | Big East | Away | W | 70–57 | Regular | Madison Square Garden |
| 92 | 2017-01-16 | 2016–17 | #1 Villanova | Seton Hall | Big East | Home | W | 76–46 | Regular | Finneran Pavilion |
| 93 | 2017-01-21 | 2016–17 | #1 Villanova | Providence | Big East | Home | W | 78–68 | Regular | Wells Fargo Arena |
| 94 | 2017-01-24 | 2016–17 | #1 Villanova | Marquette | Big East | Away | L | 72–74 | Regular | Bradley Center |
| 95 | 2017-01-29 | 2016–17 | #1 Villanova | #12 Virginia | ACC | Home | W | 61–59 | Regular | Finneran Pavilion |
| 96 | 2017-02-01 | 2016–17 | #4 Villanova | Providence | Big East | Away | W | 66–57 | Regular | Amica Mutual Pavilion |
| 97 | 2017-02-04 | 2016–17 | #4 Villanova | St. John's (NY) | Big East | Home | W | 92–79 | Regular | Xfinity Mobile Arena |
| 98 | 2017-02-07 | 2016–17 | #2 Villanova | Georgetown | Big East | Home | W | 75–64 | Regular | Finneran Pavilion |
| 99 | 2017-02-11 | 2016–17 | #2 Villanova | #24 Xavier | Big East | Away | W | 73–57 | Regular | Cintas Center |
| 100 | 2017-02-13 | 2016–17 | #2 Villanova | DePaul | Big East | Away | W | 75–62 | Regular | Allstate Arena |
| 101 | 2017-02-18 | 2016–17 | #2 Villanova | Seton Hall | Big East | Away | W | 92–70 | Regular | Prudential Center |
| 102 | 2017-02-22 | 2016–17 | #2 Villanova | #22 Butler | Big East | Home | L | 66–74 | Regular | Finneran Pavilion |
| 103 | 2017-02-25 | 2016–17 | #2 Villanova | #23 Creighton | Big East | Home | W | 79–63 | Regular | Finneran Pavilion |
| 104 | 2017-03-04 | 2016–17 | #2 Villanova | Georgetown | Big East | Away | W | 81–55 | Regular | Capital One Arena |
| 105 | 2017-03-09 | 2016–17 | #2 Villanova | St. John's (NY) | Big East | Neutral | W | 108–67 | Conf. Tourn. | Madison Square Garden |
| 106 | 2017-03-10 | 2016–17 | #2 Villanova | Seton Hall | Big East | Neutral | W | 55–53 | Conf. Tourn. | Madison Square Garden |
| 107 | 2017-03-11 | 2016–17 | #2 Villanova | Creighton | Big East | Neutral | W | 74–60 | Conf. Tourn. | Madison Square Garden |
| 108 | 2017-11-14 | 2017–18 | #5 Villanova | Nicholls State | Southland | Home | W | 113–77 | Regular | Xfinity Mobile Arena |
| 109 | 2017-11-17 | 2017–18 | #5 Villanova | Lafayette | Patriot | Neutral | W | 104–57 | Regular | PPL Center |
| 110 | 2017-11-22 | 2017–18 | #5 Villanova | Western Kentucky | CUSA | Neutral | W | 66–58 | Regular | Imperial Arena |
| 111 | 2017-11-23 | 2017–18 | #5 Villanova | Tennessee | SEC | Neutral | W | 85–76 | Regular | Imperial Arena |
| 112 | 2017-11-24 | 2017–18 | #5 Villanova | Northern Iowa | Missouri Valley | Neutral | W | 64–50 | Regular | Imperial Arena |
| 113 | 2017-11-29 | 2017–18 | #4 Villanova | Pennsylvania | Ivy | Home | W | 90–62 | Regular | Jake Nevin Field House |
| 114 | 2017-12-02 | 2017–18 | #4 Villanova | Saint Joseph's | A10 | Away | W | 94–53 | Regular | Hagan Arena |
| 115 | 2017-12-05 | 2017–18 | #4 Villanova | #12 Gonzaga | WCC | Neutral | W | 88–72 | Regular | Madison Square Garden |
| 116 | 2017-12-10 | 2017–18 | #4 Villanova | La Salle | A10 | Home | W | 77–68 | Regular | Xfinity Mobile Arena |
| 117 | 2017-12-13 | 2017–18 | #1 Villanova | Temple | AAC | Away | W | 87–67 | Regular | Liacouras Center |
| 118 | 2017-12-22 | 2017–18 | #1 Villanova | Hofstra | Colonial | Neutral | W | 95–71 | Regular | Nassau Coliseum |
| 119 | 2017-12-27 | 2017–18 | #1 Villanova | DePaul | Big East | Away | W | 103–85 | Regular | Wintrust Arena |
| 120 | 2017-12-30 | 2017–18 | #1 Villanova | Butler | Big East | Away | L | 93–101 | Regular | Hinkle Fieldhouse |
| 121 | 2018-01-06 | 2017–18 | #3 Villanova | Marquette | Big East | Home | W | 100–90 | Regular | Xfinity Mobile Arena |
| 122 | 2018-01-10 | 2017–18 | #1 Villanova | #10 Xavier | Big East | Home | W | 89–65 | Regular | Xfinity Mobile Arena |
| 123 | 2018-01-13 | 2017–18 | #1 Villanova | St. John's (NY) | Big East | Away | W | 78–71 | Regular | Madison Square Garden |
| 124 | 2018-01-17 | 2017–18 | #1 Villanova | Georgetown | Big East | Away | W | 88–56 | Regular | Capital One Arena |
| 125 | 2018-01-20 | 2017–18 | #1 Villanova | Connecticut | AAC | Away | W | 81–61 | Regular | PeoplesBank Arena |
| 126 | 2018-01-23 | 2017–18 | #1 Villanova | Providence | Big East | Home | W | 89–69 | Regular | Xfinity Mobile Arena |
| 127 | 2018-01-28 | 2017–18 | #1 Villanova | Marquette | Big East | Away | W | 85–82 | Regular | Bradley Center |
| 128 | 2018-02-01 | 2017–18 | #1 Villanova | Creighton | Big East | Home | W | 98–78 | Regular | Xfinity Mobile Arena |
| 129 | 2018-02-04 | 2017–18 | #1 Villanova | Seton Hall | Big East | Home | W | 92–76 | Regular | Xfinity Mobile Arena |
| 130 | 2018-02-07 | 2017–18 | #1 Villanova | St. John's (NY) | Big East | Home | L | 75–79 | Regular | Xfinity Mobile Arena |
| 131 | 2018-02-10 | 2017–18 | #1 Villanova | Butler | Big East | Home | W | 86–75 | Regular | Xfinity Mobile Arena |
| 132 | 2018-02-14 | 2017–18 | #3 Villanova | Providence | Big East | Away | L | 71–76 | Regular | Amica Mutual Pavilion |
| 133 | 2018-02-17 | 2017–18 | #3 Villanova | #4 Xavier | Big East | Away | W | 95–79 | Regular | Cintas Center |
| 134 | 2018-02-21 | 2017–18 | #3 Villanova | DePaul | Big East | Home | W | 93–62 | Regular | Xfinity Mobile Arena |
| 135 | 2018-02-24 | 2017–18 | #3 Villanova | Creighton | Big East | Away | L | 83–89 OT | Regular | CHI Health Center Omaha |
| 136 | 2018-02-28 | 2017–18 | #4 Villanova | Seton Hall | Big East | Away | W | 69–68 OT | Regular | Prudential Center |
| 137 | 2018-03-03 | 2017–18 | #4 Villanova | Georgetown | Big East | Home | W | 97–73 | Regular | Xfinity Mobile Arena |
| 138 | 2018-03-08 | 2017–18 | #2 Villanova | Marquette | Big East | Neutral | W | 94–70 | Conf. Tourn. | Madison Square Garden |
| 139 | 2018-03-09 | 2017–18 | #2 Villanova | Butler | Big East | Neutral | W | 87–68 | Conf. Tourn. | Madison Square Garden |
| 140 | 2018-03-10 | 2017–18 | #2 Villanova | Providence | Big East | Neutral | W | 76–66 OT | Conf. Tourn. | Madison Square Garden |
| 141 | 2020-11-25 | 2020–21 | #3 Villanova | Boston College | ACC | Neutral | W | 76–67 | Regular | Mohegan Sun Arena |
| 142 | 2020-11-26 | 2020–21 | #3 Villanova | #18 Arizona State | Pacific 12 | Neutral | W | 83–74 | Regular | Mohegan Sun Arena |
| 143 | 2020-11-28 | 2020–21 | #3 Villanova | Virginia Tech | ACC | Neutral | L | 73–81 OT | Regular | Mohegan Sun Arena |
| 144 | 2020-12-23 | 2020–21 | #5 Villanova | Marquette | Big East | Away | W | 85–68 | Regular | Fiserv Forum |
| 145 | 2021-01-19 | 2020–21 | #3 Villanova | Seton Hall | Big East | Home | W | 76–74 | Regular | Finneran Pavilion |
| 146 | 2021-01-23 | 2020–21 | #3 Villanova | Providence | Big East | Home | W | 71–56 | Regular | Finneran Pavilion |
| 147 | 2021-01-30 | 2020–21 | #3 Villanova | Seton Hall | Big East | Away | W | 80–72 | Regular | Prudential Center |
| 148 | 2021-02-03 | 2020–21 | #3 Villanova | St. John's (NY) | Big East | Away | L | 59–70 | Regular | Carnesecca Arena |
| 149 | 2021-02-07 | 2020–21 | #3 Villanova | Georgetown | Big East | Home | W | 84–74 | Regular | Finneran Pavilion |
| 150 | 2021-02-10 | 2020–21 | #5 Villanova | Marquette | Big East | Home | W | 96–64 | Regular | Finneran Pavilion |
| 151 | 2021-02-13 | 2020–21 | #5 Villanova | #19 Creighton | Big East | Away | L | 70–86 | Regular | CHI Health Center Omaha |
| 152 | 2021-11-09 | 2021–22 | #4 Villanova | Mount St. Mary's | NEC | Home | W | 91–51 | Regular | Finneran Pavilion |
| 153 | 2021-11-12 | 2021–22 | #4 Villanova | #2 UCLA | Pacific 12 | Away | L | 77–86 OT | Regular | Pauley Pavilion |
| 154 | 2021-11-16 | 2021–22 | #5 Villanova | Howard | MEAC | Home | W | 100–81 | Regular | Finneran Pavilion |
| 155 | 2021-11-20 | 2021–22 | #5 Villanova | #17 Tennessee | SEC | Neutral | W | 71–53 | Regular | Mohegan Sun Arena |
| 156 | 2021-11-21 | 2021–22 | #5 Villanova | #6 Purdue | B10 | Neutral | L | 74–80 | Regular | Mohegan Sun Arena |