DePaul 2010–11
Coach: Oliver Purnell (7-24)
Big East Conference
7-24
overall
7-23
regular season
1-17
in conference
Games (31)
| # | Date | School | Opponent | Opp. Conf. | Loc | W/L | Score | Type | Arena |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 2010-11-14 | DePaul | Chicago State | Great West | Home | W | 114–81 | Regular | Allstate Arena |
| 2 | 2010-11-16 | DePaul | Western Carolina | SoCon | Home | L | 64–69 | Regular | Allstate Arena |
| 3 | 2010-11-25 | DePaul | Oklahoma State | B12 | Neutral | L | 56–60 | Regular | Anaheim Convention Center |
| 4 | 2010-11-26 | DePaul | Cal State Northridge | Big West | Neutral | L | 66–88 | Regular | Anaheim Convention Center |
| 5 | 2010-11-28 | DePaul | Stanford | Pacific 10 | Neutral | L | 74–81 OT | Regular | Anaheim Convention Center |
| 6 | 2010-12-02 | DePaul | Northern Illinois | MAC | Home | W | 86–84 | Regular | Allstate Arena |
| 7 | 2010-12-05 | DePaul | Central Michigan | MAC | Home | W | 71–62 | Regular | Allstate Arena |
| 8 | 2010-12-08 | DePaul | Indiana State | Missouri Valley | Away | L | 51–73 | Regular | Hulman Center |
| 9 | 2010-12-11 | DePaul | Ball State | MAC | Home | L | 77–79 OT | Regular | Allstate Arena |
| 10 | 2010-12-14 | DePaul | Milwaukee | Horizon | Home | W | 61–47 | Regular | Allstate Arena |
| 11 | 2010-12-18 | DePaul | Loyola (IL) | Horizon | Home | W | 81–74 | Regular | Allstate Arena |
| 12 | 2010-12-22 | DePaul | Florida Atlantic | Sun Belt | Home | W | 71–62 | Regular | Allstate Arena |
| 13 | 2010-12-28 | DePaul | Cincinnati | Big East | Away | L | 60–76 | Regular | Fifth Third Arena |
| 14 | 2011-01-01 | DePaul | #9 Georgetown | Big East | Away | L | 75–86 | Regular | Capital One Arena |
| 15 | 2011-01-04 | DePaul | West Virginia | Big East | Home | L | 65–67 | Regular | Allstate Arena |
| 16 | 2011-01-12 | DePaul | Seton Hall | Big East | Home | L | 67–78 | Regular | Allstate Arena |
| 17 | 2011-01-15 | DePaul | #10 Connecticut | Big East | Home | L | 62–82 | Regular | Allstate Arena |
| 18 | 2011-01-18 | DePaul | Marquette | Big East | Away | L | 64–94 | Regular | Bradley Center |
| 19 | 2011-01-22 | DePaul | #5 Pittsburgh | Big East | Home | L | 50–80 | Regular | Allstate Arena |
| 20 | 2011-01-27 | DePaul | South Florida | Big East | Away | L | 60–71 | Regular | Yuengling Center |
| 21 | 2011-02-03 | DePaul | #9 Notre Dame | Big East | Home | L | 58–83 | Regular | Allstate Arena |
| 22 | 2011-02-05 | DePaul | #15 Louisville | Big East | Away | L | 57–61 | Regular | KFC Yum! Center |
| 23 | 2011-02-08 | DePaul | Cincinnati | Big East | Home | L | 68–71 | Regular | Allstate Arena |
| 24 | 2011-02-12 | DePaul | #25 West Virginia | Big East | Away | L | 71–82 | Regular | Hope Coliseum |
| 25 | 2011-02-17 | DePaul | Providence | Big East | Away | W | 79–76 | Regular | Amica Mutual Pavilion |
| 26 | 2011-02-19 | DePaul | #15 Villanova | Big East | Home | L | 75–77 OT | Regular | Allstate Arena |
| 27 | 2011-02-23 | DePaul | #23 St. John's (NY) | Big East | Away | L | 51–76 | Regular | Carnesecca Arena |
| 28 | 2011-02-26 | DePaul | South Florida | Big East | Home | L | 76–86 | Regular | Allstate Arena |
| 29 | 2011-03-02 | DePaul | Rutgers | Big East | Home | L | 64–68 | Regular | Allstate Arena |
| 30 | 2011-03-05 | DePaul | #12 Syracuse | Big East | Away | L | 59–107 | Regular | Carrier Dome |
| 31 | 2011-03-08 | DePaul | #21 Connecticut | Big East | Neutral | L | 71–97 | Conf. Tourn. | Madison Square Garden |