Depaul 2025–26
Coach: Chris Holtmann (16-16)
Big East Conference
16-16
overall
16-15
regular season
8-12
in conference
Games (32)
| # | Date | School | Opponent | Opp. Conf. | Loc | W/L | Score | Type | Arena |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | Depaul | Chicago State | NEC | Home | W | 92–62 | Regular | Wintrust Arena |
| 2 | 2025-11-07 | Depaul | Stonehill | NEC | Home | W | 72–64 | Regular | Wintrust Arena |
| 3 | 2025-11-11 | Depaul | Buffalo | MAC | Home | L | 53–66 | Regular | Wintrust Arena |
| 4 | 2025-11-14 | Depaul | Northwestern | B10 | Home | L | 79–81 | Regular | Wintrust Arena |
| 5 | 2025-11-18 | Depaul | Gardner Webb | Big South | Home | W | 93–62 | Regular | Wintrust Arena |
| 6 | 2025-11-23 | Depaul | Detroit Mercy | Horizon | Home | W | 95–75 | Regular | Wintrust Arena |
| 7 | 2025-11-28 | Depaul | Georgia Tech | ACC | Neutral | W | 75–61 | Regular | The Arena at Northwest Florida State College |
| 8 | 2025-11-29 | Depaul | LSU | SEC | Neutral | L | 63–96 | Regular | The Arena at Northwest Florida State College |
| 9 | 2025-12-06 | Depaul | Arkansas Pine Bluff | SWAC | Home | W | 76–72 | Regular | Wintrust Arena |
| 10 | 2025-12-09 | Depaul | Morgan State | MEAC | Home | W | 92–49 | Regular | Wintrust Arena |
| 11 | 2025-12-13 | Depaul | Wichita State | American | Away | W | 61–58 | Regular | Charles Koch Arena |
| 12 | 2025-12-16 | Depaul | #22 St. Johns (NY) | Big East | Away | L | 66–79 | Regular | Carnesecca Arena |
| 13 | 2025-12-21 | Depaul | #5 UConn | Big East | Home | L | 54–72 | Regular | Wintrust Arena |
| 14 | 2025-12-31 | Depaul | Villanova | Big East | Away | L | 66–71 | Regular | Finneran Pavilion |
| 15 | 2026-01-03 | Depaul | Xavier | Big East | Home | W | 86–77 | Regular | Wintrust Arena |
| 16 | 2026-01-06 | Depaul | Georgetown | Big East | Home | W | 56–50 | Regular | Wintrust Arena |
| 17 | 2026-01-10 | Depaul | #4 UConn | Big East | Away | L | 60–72 | Regular | PeoplesBank Arena |
| 18 | 2026-01-16 | Depaul | Marquette | Big East | Home | W | 80–75 | Regular | Wintrust Arena |
| 19 | 2026-01-20 | Depaul | Butler | Big East | Away | L | 80–87 | Regular | Hinkle Fieldhouse |
| 20 | 2026-01-24 | Depaul | Seton Hall | Big East | Home | W | 67–60 | Regular | Wintrust Arena |
| 21 | 2026-01-28 | Depaul | Georgetown | Big East | Away | L | 61–70 | Regular | Capital One Arena |
| 22 | 2026-01-31 | Depaul | Xavier | Big East | Away | L | 66–68 | Regular | Cintas Center |
| 23 | 2026-02-03 | Depaul | #22 St. Johns (NY) | Big East | Home | L | 56–68 | Regular | Wintrust Arena |
| 24 | 2026-02-07 | Depaul | Providence | Big East | Away | L | 72–90 | Regular | Amica Mutual Pavilion |
| 25 | 2026-02-11 | Depaul | Creighton | Big East | Home | W | 72–71 | Regular | Wintrust Arena |
| 26 | 2026-02-18 | Depaul | Seton Hall | Big East | Away | W | 69–57 | Regular | Prudential Center |
| 27 | 2026-02-21 | Depaul | Providence | Big East | Home | L | 68–71 | Regular | Wintrust Arena |
| 28 | 2026-02-25 | Depaul | Creighton | Big East | Away | W | 72–71 | Regular | CHI Health Center Omaha |
| 29 | 2026-03-01 | Depaul | Marquette | Big East | Away | W | 62–51 | Regular | Fiserv Forum |
| 30 | 2026-03-04 | Depaul | Villanova | Big East | Home | L | 57–76 | Regular | Wintrust Arena |
| 31 | 2026-03-07 | Depaul | Butler | Big East | Home | L | 71–81 | Regular | Wintrust Arena |
| 32 | 2026-03-11 | Depaul | Georgetown | Big East | Neutral | L | 56–63 | Conf. Tourn. | Madison Square Garden |