Tom Izzo — Non-Conference Game Record
297–88
77.1%
win rate
+12.2
avg margin
385
games
Games (385)
| # | Date | Season | School | Opponent | Opp. Conf. | Loc | W/L | Score | Type | Arena |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2000-11-19 | 2000–01 | #3 Michigan State | Oakland | Mid-Continent | Home | W | 97–61 | Regular | Breslin Events Center |
| 2 | 2000-11-24 | 2000–01 | #4 Michigan State | Cornell | Ivy | Home | W | 89–56 | Regular | Breslin Events Center |
| 3 | 2000-11-25 | 2000–01 | #4 Michigan State | Eastern Washington | Big Sky | Home | W | 83–61 | Regular | Breslin Events Center |
| 4 | 2000-11-29 | 2000–01 | #3 Michigan State | #6 North Carolina | ACC | Home | W | 77–64 | Regular | Breslin Events Center |
| 5 | 2000-12-02 | 2000–01 | #3 Michigan State | Illinois-Chicago | Midwestern Collegiate | Home | W | 97–53 | Regular | Breslin Events Center |
| 6 | 2000-12-06 | 2000–01 | #2 Michigan State | #8 Florida | SEC | Home | W | 99–83 | Regular | Breslin Events Center |
| 7 | 2000-12-09 | 2000–01 | #2 Michigan State | Loyola (IL) | Midwestern Collegiate | Away | W | 103–71 | Regular | Joseph J. Gentile Arena |
| 8 | 2000-12-16 | 2000–01 | #2 Michigan State | Kentucky | SEC | Home | W | 46–45 | Regular | Breslin Events Center |
| 9 | 2000-12-19 | 2000–01 | #2 Michigan State | #8 Seton Hall | Big East | Neutral | W | 72–57 | Regular | Meadowlands Arena |
| 10 | 2000-12-27 | 2000–01 | #1 Michigan State | Bowling Green | MAC | Home | W | 85–69 | Regular | Breslin Events Center |
| 11 | 2000-12-30 | 2000–01 | #1 Michigan State | Wright State | Midwestern Collegiate | Home | W | 88–61 | Regular | Breslin Events Center |
| 12 | 2001-03-16 | 2000–01 | #3 Michigan State | Alabama State | SWAC | Neutral | W | 69–35 | NCAA | The Pyramid |
| 13 | 2001-03-18 | 2000–01 | #3 Michigan State | Fresno State | WAC | Neutral | W | 81–65 | NCAA | The Pyramid |
| 14 | 2001-03-23 | 2000–01 | #3 Michigan State | Gonzaga | WCC | Neutral | W | 77–62 | NCAA | Georgia Dome |
| 15 | 2001-03-25 | 2000–01 | #3 Michigan State | Temple | A10 | Neutral | W | 69–62 | NCAA | Georgia Dome |
| 16 | 2001-03-31 | 2000–01 | #3 Michigan State | #5 Arizona Wildcats | Pacific 10 | Neutral | L | 61–80 | NCAA | Hubert H. Humphrey Metrodome |
| 17 | 2001-11-12 | 2001–02 | #15 Michigan State | Detroit Mercy | Horizon | Home | W | 80–70 | Regular | Breslin Events Center |
| 18 | 2001-11-14 | 2001–02 | #15 Michigan State | #25 Oklahoma | B12 | Home | W | 67–55 | Regular | Breslin Events Center |
| 19 | 2001-11-21 | 2001–02 | #13 Michigan State | #18 Syracuse | Big East | Neutral | L | 58–69 | Regular | Madison Square Garden |
| 20 | 2001-11-23 | 2001–02 | #13 Michigan State | #23 Fresno State | WAC | Neutral | L | 58–63 | Regular | Madison Square Garden |
| 21 | 2001-11-30 | 2001–02 | #22 Michigan State | Purdue Fort Wayne | - | Home | W | 81–68 | Regular | Breslin Events Center |
| 22 | 2001-12-01 | 2001–02 | #22 Michigan State | Lamar | Southland | Home | W | 80–71 | Regular | Breslin Events Center |
| 23 | 2001-12-05 | 2001–02 | #24 Michigan State | #6 Florida | SEC | Away | L | 70–74 | Regular | Stephen C. O'Connell Center |
| 24 | 2001-12-09 | 2001–02 | #24 Michigan State | Nicholls State | Southland | Home | W | 92–38 | Regular | Breslin Events Center |
| 25 | 2001-12-15 | 2001–02 | #23 Michigan State | #6 Arizona Wildcats | Pacific 10 | Home | W | 74–60 | Regular | Breslin Events Center |
| 26 | 2001-12-17 | 2001–02 | #17 Michigan State | UNC Asheville | Big South | Home | W | 76–56 | Regular | Breslin Events Center |
| 27 | 2001-12-19 | 2001–02 | #17 Michigan State | Oakland | Mid-Continent | Home | W | 78–50 | Regular | Breslin Events Center |
| 28 | 2001-12-22 | 2001–02 | #17 Michigan State | Seton Hall | Big East | Home | W | 68–64 | Regular | Breslin Events Center |
| 29 | 2001-12-29 | 2001–02 | #13 Michigan State | #16 Stanford | Pacific 10 | Neutral | L | 64–75 | Regular | Oakland Arena |
| 30 | 2002-03-15 | 2001–02 | #25 Michigan State | NC State | ACC | Neutral | L | 58–69 | NCAA | Capital One Arena |
| 31 | 2002-11-22 | 2002–03 | #9 Michigan State | UNC Asheville | Big South | Home | W | 66–52 | Regular | Breslin Events Center |
| 32 | 2002-11-28 | 2002–03 | #9 Michigan State | Montana | Big Sky | Neutral | W | 80–60 | Regular | Sullivan Arena |
| 33 | 2002-11-29 | 2002–03 | #9 Michigan State | Villanova | Big East | Neutral | L | 73–81 | Regular | Sullivan Arena |
| 34 | 2002-11-30 | 2002–03 | #9 Michigan State | Oklahoma State | B12 | Neutral | L | 61–64 | Regular | Sullivan Arena |
| 35 | 2002-12-04 | 2002–03 | #21 Michigan State | #22 Virginia | ACC | Home | W | 82–75 | Regular | Breslin Events Center |
| 36 | 2002-12-08 | 2002–03 | #21 Michigan State | Cleveland State | Horizon | Home | W | 79–47 | Regular | Breslin Events Center |
| 37 | 2002-12-14 | 2002–03 | #21 Michigan State | #12 Kentucky | SEC | Away | W | 71–67 | Regular | Rupp Arena |
| 38 | 2002-12-17 | 2002–03 | #15 Michigan State | Loyola (IL) | Horizon | Home | W | 80–54 | Regular | Breslin Events Center |
| 39 | 2002-12-21 | 2002–03 | #15 Michigan State | South Florida | CUSA | Home | W | 65–56 | Regular | Breslin Events Center |
| 40 | 2002-12-28 | 2002–03 | #15 Michigan State | Jacksonville State | ASUN | Home | W | 76–52 | Regular | Breslin Events Center |
| 41 | 2002-12-30 | 2002–03 | #14 Michigan State | Toledo | MAC | Home | L | 76–81 | Regular | Breslin Events Center |
| 42 | 2003-01-04 | 2002–03 | #14 Michigan State | #10 Oklahoma | B12 | Neutral | L | 58–60 | Regular | Paycom Center |
| 43 | 2003-02-23 | 2002–03 | #25 Michigan State | #15 Syracuse | Big East | Home | L | 75–76 | Regular | Breslin Events Center |
| 44 | 2003-03-21 | 2002–03 | #25 Michigan State | Colorado | B12 | Neutral | W | 79–64 | NCAA | Benchmark International Arena |
| 45 | 2003-03-23 | 2002–03 | #25 Michigan State | #10 Florida | SEC | Neutral | W | 68–46 | NCAA | Benchmark International Arena |
| 46 | 2003-03-28 | 2002–03 | #25 Michigan State | #17 Maryland | ACC | Neutral | W | 60–58 | NCAA | Alamodome |
| 47 | 2003-03-30 | 2002–03 | #25 Michigan State | #5 Texas | B12 | Neutral | L | 76–85 | NCAA | Alamodome |
| 48 | 2003-11-21 | 2003–04 | #3 Michigan State | Bucknell | Patriot | Home | W | 64–52 | Regular | Breslin Events Center |
| 49 | 2003-11-25 | 2003–04 | #3 Michigan State | #6 Kansas | B12 | Away | L | 74–81 | Regular | Allen Fieldhouse |
| 50 | 2003-11-29 | 2003–04 | #3 Michigan State | Pennsylvania | Ivy | Home | W | 77–52 | Regular | Breslin Events Center |
| 51 | 2003-11-30 | 2003–04 | #3 Michigan State | DePaul | CUSA | Home | W | 89–81 | Regular | Breslin Events Center |
| 52 | 2003-12-03 | 2003–04 | #5 Michigan State | #6 Duke | ACC | Home | L | 50–72 | Regular | Breslin Events Center |
| 53 | 2003-12-06 | 2003–04 | #5 Michigan State | #14 Oklahoma | B12 | Neutral | L | 77–80 OT | Regular | The Palace of Auburn Hills |
| 54 | 2003-12-13 | 2003–04 | #21 Michigan State | #8 Kentucky | SEC | Neutral | L | 74–79 | Regular | Ford Field |
| 55 | 2003-12-16 | 2003–04 | #21 Michigan State | South Florida | CUSA | Home | W | 73–60 | Regular | Breslin Events Center |
| 56 | 2003-12-20 | 2003–04 | #21 Michigan State | UCLA | Pacific 10 | Away | L | 58–64 | Regular | Pauley Pavilion |
| 57 | 2003-12-30 | 2003–04 | #21 Michigan State | Coppin State | MEAC | Home | W | 78–72 | Regular | Breslin Events Center |
| 58 | 2004-01-03 | 2003–04 | #21 Michigan State | #17 Syracuse | Big East | Away | L | 83–96 | Regular | Carrier Dome |
| 59 | 2004-03-18 | 2003–04 | #21 Michigan State | Nevada | WAC | Neutral | L | 66–72 | NCAA | Climate Pledge Arena |
| 60 | 2004-11-19 | 2004–05 | #13 Michigan State | Florida A&M | MEAC | Home | W | 104–72 | Regular | Breslin Events Center |
| 61 | 2004-11-23 | 2004–05 | #10 Michigan State | Green Bay | Horizon | Home | W | 104–46 | Regular | Breslin Events Center |
| 62 | 2004-11-27 | 2004–05 | #10 Michigan State | Nicholls State | Southland | Home | W | 102–52 | Regular | Breslin Events Center |
| 63 | 2004-11-30 | 2004–05 | #11 Michigan State | #10 Duke | ACC | Away | L | 74–81 | Regular | Cameron Indoor Stadium |
| 64 | 2004-12-04 | 2004–05 | #11 Michigan State | George Washington | A10 | Away | L | 83–96 | Regular | Charles E. Smith Center |
| 65 | 2004-12-05 | 2004–05 | #11 Michigan State | George Mason | Colonial | Neutral | W | 66–60 | Regular | Capital One Arena |
| 66 | 2004-12-11 | 2004–05 | #20 Michigan State | Stanford | Pacific 10 | Neutral | W | 78–53 | Regular | The Palace of Auburn Hills |
| 67 | 2004-12-18 | 2004–05 | #21 Michigan State | Delaware State | MEAC | Home | W | 63–45 | Regular | Breslin Events Center |
| 68 | 2004-12-21 | 2004–05 | #23 Michigan State | UCLA | Pacific 10 | Home | W | 76–64 | Regular | Breslin Events Center |
| 69 | 2004-12-29 | 2004–05 | #23 Michigan State | UNC Asheville | Big South | Home | W | 92–63 | Regular | Breslin Events Center |
| 70 | 2005-01-29 | 2004–05 | #15 Michigan State | Oakland | Mid-Continent | Home | W | 92–75 | Regular | Breslin Events Center |
| 71 | 2005-03-18 | 2004–05 | #15 Michigan State | Old Dominion | Colonial | Neutral | W | 89–81 | NCAA | DCU Center |
| 72 | 2005-03-20 | 2004–05 | #15 Michigan State | Vermont | Am. East | Neutral | W | 72–61 | NCAA | DCU Center |
| 73 | 2005-03-25 | 2004–05 | #15 Michigan State | #3 Duke | ACC | Neutral | W | 78–68 | NCAA | Frank Erwin Center |
| 74 | 2005-03-27 | 2004–05 | #15 Michigan State | #7 Kentucky | SEC | Neutral | W | 94–88 2OT | NCAA | Frank Erwin Center |
| 75 | 2005-04-02 | 2004–05 | #15 Michigan State | #2 North Carolina | ACC | Neutral | L | 71–87 | NCAA | The Dome at America's Center |
| 76 | 2005-11-19 | 2005–06 | #4 Michigan State | Hawaii | WAC | Away | L | 62–84 | Regular | Stan Sheriff Center |
| 77 | 2005-11-21 | 2005–06 | #12 Michigan State | Chaminade | - | Neutral | W | 89–67 | Regular | Lahaina Civic Center |
| 78 | 2005-11-22 | 2005–06 | #12 Michigan State | #8 Gonzaga | WCC | Neutral | L | 106–109 3OT | Regular | Lahaina Civic Center |
| 79 | 2005-11-23 | 2005–06 | #12 Michigan State | #9 Arizona Wildcats | Pacific 10 | Neutral | W | 74–71 OT | Regular | Lahaina Civic Center |
| 80 | 2005-11-27 | 2005–06 | #12 Michigan State | Purdue Fort Wayne | Independent | Home | W | 84–73 | Regular | Breslin Events Center |
| 81 | 2005-11-30 | 2005–06 | #13 Michigan State | Georgia Tech | ACC | Home | W | 88–86 | Regular | Breslin Events Center |
| 82 | 2005-12-03 | 2005–06 | #13 Michigan State | Little Rock | Sun Belt | Neutral | W | 72–67 | Regular | Van Andel Arena |
| 83 | 2005-12-06 | 2005–06 | #14 Michigan State | #6 Boston College | ACC | Neutral | W | 77–70 | Regular | Madison Square Garden |
| 84 | 2005-12-10 | 2005–06 | #14 Michigan State | Wichita State | Missouri Valley | Neutral | W | 83–64 | Regular | The Palace of Auburn Hills |
| 85 | 2005-12-16 | 2005–06 | #12 Michigan State | Cleveland State | Horizon | Home | W | 83–75 | Regular | Breslin Events Center |
| 86 | 2005-12-18 | 2005–06 | #12 Michigan State | Florida International | Sun Belt | Home | W | 85–58 | Regular | Breslin Events Center |
| 87 | 2005-12-21 | 2005–06 | #10 Michigan State | Green Bay | Horizon | Away | W | 98–69 | Regular | Resch Center |
| 88 | 2005-12-28 | 2005–06 | #9 Michigan State | Tennessee Tech | OVC | Home | W | 80–63 | Regular | Breslin Events Center |
| 89 | 2005-12-31 | 2005–06 | #9 Michigan State | Coppin State | MEAC | Home | W | 78–54 | Regular | Breslin Events Center |
| 90 | 2006-03-17 | 2005–06 | #25 Michigan State | George Mason | Colonial | Neutral | L | 65–75 | NCAA | University of Dayton Arena |
| 91 | 2006-11-08 | 2006–07 | Michigan State | Brown | Ivy | Home | W | 45–34 | Regular | Breslin Events Center |
| 92 | 2006-11-09 | 2006–07 | Michigan State | Youngstown State | Horizon | Home | W | 86–61 | Regular | Breslin Events Center |
| 93 | 2006-11-12 | 2006–07 | Michigan State | The Citadel | SoCon | Home | W | 73–41 | Regular | Breslin Events Center |
| 94 | 2006-11-16 | 2006–07 | Michigan State | #19 Texas | B12 | Neutral | W | 63–61 | Regular | Madison Square Garden |
| 95 | 2006-11-17 | 2006–07 | Michigan State | Maryland | ACC | Neutral | L | 60–62 | Regular | Madison Square Garden |
| 96 | 2006-11-21 | 2006–07 | Michigan State | Vermont | Am. East | Home | W | 66–46 | Regular | Breslin Events Center |
| 97 | 2006-11-25 | 2006–07 | Michigan State | Oakland | Mid-Continent | Home | W | 71–53 | Regular | Breslin Events Center |
| 98 | 2006-11-29 | 2006–07 | Michigan State | Boston College | ACC | Away | L | 58–65 | Regular | Conte Forum |
| 99 | 2006-12-03 | 2006–07 | Michigan State | Bradley | Missouri Valley | Home | W | 82–53 | Regular | Breslin Events Center |
| 100 | 2006-12-06 | 2006–07 | Michigan State | Purdue Fort Wayne | Independent | Home | W | 80–43 | Regular | Breslin Events Center |
| 101 | 2006-12-09 | 2006–07 | Michigan State | Brigham Young | Mountain West | Neutral | W | 76–61 | Regular | The Palace of Auburn Hills |
| 102 | 2006-12-16 | 2006–07 | Michigan State | Chicago State | Independent | Home | W | 69–61 | Regular | Breslin Events Center |
| 103 | 2006-12-19 | 2006–07 | Michigan State | Belmont | ASUN | Home | W | 67–58 | Regular | Breslin Events Center |
| 104 | 2006-12-23 | 2006–07 | Michigan State | Green Bay | Horizon | Home | W | 76–64 | Regular | Breslin Events Center |
| 105 | 2006-12-30 | 2006–07 | Michigan State | Loyola (MD) | MAAC | Home | W | 74–61 | Regular | Breslin Events Center |
| 106 | 2007-03-15 | 2006–07 | Michigan State | #20 Marquette | Big East | Neutral | W | 61–49 | NCAA | Lawrence Joel Veterans Memorial Coliseum |
| 107 | 2007-03-17 | 2006–07 | Michigan State | #4 North Carolina | ACC | Neutral | L | 67–81 | NCAA | Lawrence Joel Veterans Memorial Coliseum |
| 108 | 2007-11-13 | 2007–08 | #12 Michigan State | Chicago State | Independent | Home | W | 86–53 | Regular | Breslin Events Center |
| 109 | 2007-11-14 | 2007–08 | #12 Michigan State | Louisiana-Monroe | Sun Belt | Home | W | 83–65 | Regular | Breslin Events Center |
| 110 | 2007-11-19 | 2007–08 | #10 Michigan State | Missouri | B12 | Neutral | W | 86–83 | Regular | T-Mobile Center |
| 111 | 2007-11-20 | 2007–08 | #10 Michigan State | #2 UCLA | Pacific 10 | Neutral | L | 63–68 | Regular | T-Mobile Center |
| 112 | 2007-11-24 | 2007–08 | #10 Michigan State | Oakland | Summit | Home | W | 75–71 | Regular | Breslin Events Center |
| 113 | 2007-11-28 | 2007–08 | #10 Michigan State | #24 NC State | ACC | Home | W | 81–58 | Regular | Breslin Events Center |
| 114 | 2007-12-01 | 2007–08 | #10 Michigan State | Jacksonville | ASUN | Home | W | 80–51 | Regular | Breslin Events Center |
| 115 | 2007-12-04 | 2007–08 | #9 Michigan State | Bradley | Missouri Valley | Away | W | 66–61 | Regular | Carver Arena |
| 116 | 2007-12-08 | 2007–08 | #9 Michigan State | #20 Brigham Young | Mountain West | Neutral | W | 68–61 | Regular | Delta Center |
| 117 | 2007-12-15 | 2007–08 | #9 Michigan State | Purdue Fort Wayne | Summit | Home | W | 79–57 | Regular | Breslin Events Center |
| 118 | 2007-12-19 | 2007–08 | #9 Michigan State | San Jose State | WAC | Home | W | 85–45 | Regular | Breslin Events Center |
| 119 | 2007-12-22 | 2007–08 | #9 Michigan State | #4 Texas | B12 | Neutral | W | 78–72 | Regular | The Palace of Auburn Hills |
| 120 | 2007-12-29 | 2007–08 | #7 Michigan State | Green Bay | Horizon | Home | W | 93–75 | Regular | Breslin Events Center |
| 121 | 2008-03-20 | 2007–08 | #18 Michigan State | Temple | A10 | Neutral | W | 72–61 | NCAA | Ball Arena |
| 122 | 2008-03-22 | 2007–08 | #18 Michigan State | #17 Pittsburgh | Big East | Neutral | W | 65–54 | NCAA | Ball Arena |
| 123 | 2008-03-28 | 2007–08 | #18 Michigan State | #2 Memphis | CUSA | Neutral | L | 74–92 | NCAA | NRG Stadium |
| 124 | 2008-11-16 | 2008–09 | #6 Michigan State | Idaho | WAC | Home | W | 100–62 | Regular | Breslin Events Center |
| 125 | 2008-11-19 | 2008–09 | #5 Michigan State | Purdue Fort Wayne | Summit | Away | W | 70–59 | Regular | Allen County War Memorial Coliseum |
| 126 | 2008-11-27 | 2008–09 | #5 Michigan State | Maryland | ACC | Neutral | L | 62–80 | Regular | State Farm Field House |
| 127 | 2008-11-28 | 2008–09 | #5 Michigan State | Oklahoma State | B12 | Neutral | W | 94–79 | Regular | State Farm Field House |
| 128 | 2008-11-30 | 2008–09 | #5 Michigan State | Wichita State | Missouri Valley | Neutral | W | 65–57 | Regular | State Farm Field House |
| 129 | 2008-12-03 | 2008–09 | #13 Michigan State | #1 North Carolina | ACC | Neutral | L | 63–98 | Regular | Ford Field |
| 130 | 2008-12-07 | 2008–09 | #13 Michigan State | Bradley | Missouri Valley | Home | W | 75–59 | Regular | Breslin Events Center |
| 131 | 2008-12-13 | 2008–09 | #18 Michigan State | Alcorn State | SWAC | Home | W | 118–60 | Regular | Breslin Events Center |
| 132 | 2008-12-17 | 2008–09 | #19 Michigan State | The Citadel | SoCon | Home | W | 79–65 | Regular | Breslin Events Center |
| 133 | 2008-12-20 | 2008–09 | #19 Michigan State | #5 Texas | B12 | Neutral | W | 67–63 | Regular | Toyota Center |
| 134 | 2008-12-27 | 2008–09 | #11 Michigan State | Oakland | Summit | Neutral | W | 82–66 | Regular | The Palace of Auburn Hills |
| 135 | 2009-01-10 | 2008–09 | #8 Michigan State | Kansas | B12 | Home | W | 75–62 | Regular | Breslin Events Center |
| 136 | 2009-03-20 | 2008–09 | #8 Michigan State | Robert Morris | NEC | Neutral | W | 77–62 | NCAA | Hubert H. Humphrey Metrodome |
| 137 | 2009-03-22 | 2008–09 | #8 Michigan State | Southern California | Pacific 10 | Neutral | W | 74–69 | NCAA | Hubert H. Humphrey Metrodome |
| 138 | 2009-03-27 | 2008–09 | #8 Michigan State | #14 Kansas | B12 | Neutral | W | 67–62 | NCAA | Lucas Oil Stadium |
| 139 | 2009-03-29 | 2008–09 | #8 Michigan State | #1 Louisville | Big East | Neutral | W | 64–52 | NCAA | Lucas Oil Stadium |
| 140 | 2009-04-04 | 2008–09 | #8 Michigan State | #5 Connecticut | Big East | Neutral | W | 82–73 | NCAA | Ford Field |
| 141 | 2009-04-06 | 2008–09 | #8 Michigan State | #2 North Carolina | ACC | Neutral | L | 72–89 | NCAA | Ford Field |
| 142 | 2009-11-13 | 2009–10 | #2 Michigan State | Florida Gulf Coast | ASUN | Home | W | 97–58 | Regular | Breslin Events Center |
| 143 | 2009-11-17 | 2009–10 | #2 Michigan State | Gonzaga | WCC | Home | W | 75–71 | Regular | Breslin Events Center |
| 144 | 2009-11-20 | 2009–10 | #2 Michigan State | Toledo | MAC | Home | W | 75–62 | Regular | Breslin Events Center |
| 145 | 2009-11-22 | 2009–10 | #2 Michigan State | Valparaiso | Horizon | Home | W | 90–60 | Regular | Breslin Events Center |
| 146 | 2009-11-27 | 2009–10 | #2 Michigan State | Florida | SEC | Neutral | L | 74–77 | Regular | Boardwalk Hall |
| 147 | 2009-11-28 | 2009–10 | #2 Michigan State | Massachusetts | A10 | Neutral | W | 106–68 | Regular | Boardwalk Hall |
| 148 | 2009-12-01 | 2009–10 | #9 Michigan State | #10 North Carolina | ACC | Away | L | 82–89 | Regular | Dean Smith Center |
| 149 | 2009-12-04 | 2009–10 | #9 Michigan State | Wofford | SoCon | Home | W | 72–60 | Regular | Breslin Events Center |
| 150 | 2009-12-07 | 2009–10 | #12 Michigan State | The Citadel | SoCon | Away | W | 69–56 | Regular | McAlister Field House |
| 151 | 2009-12-10 | 2009–10 | #12 Michigan State | Oakland | Summit | Home | W | 88–57 | Regular | Breslin Events Center |
| 152 | 2009-12-19 | 2009–10 | #12 Michigan State | Purdue Fort Wayne | Summit | Home | W | 80–58 | Regular | Breslin Events Center |
| 153 | 2009-12-22 | 2009–10 | #9 Michigan State | #2 Texas | B12 | Away | L | 68–79 | Regular | Frank Erwin Center |
| 154 | 2009-12-30 | 2009–10 | #11 Michigan State | UT Arlington | Southland | Home | W | 87–68 | Regular | Breslin Events Center |
| 155 | 2010-03-19 | 2009–10 | #13 Michigan State | New Mexico State | WAC | Neutral | W | 70–67 | NCAA | Spokane Arena |
| 156 | 2010-03-21 | 2009–10 | #13 Michigan State | #20 Maryland | ACC | Neutral | W | 85–83 | NCAA | Spokane Arena |
| 157 | 2010-03-26 | 2009–10 | #13 Michigan State | Northern Iowa | Missouri Valley | Neutral | W | 59–52 | NCAA | The Dome at America's Center |
| 158 | 2010-03-28 | 2009–10 | #13 Michigan State | #15 Tennessee | SEC | Neutral | W | 70–69 | NCAA | The Dome at America's Center |
| 159 | 2010-04-03 | 2009–10 | #13 Michigan State | #11 Butler | Horizon | Neutral | L | 50–52 | NCAA | Lucas Oil Stadium |
| 160 | 2010-11-12 | 2010–11 | #2 Michigan State | Eastern Michigan | MAC | Home | W | 96–66 | Regular | Breslin Events Center |
| 161 | 2010-11-16 | 2010–11 | #2 Michigan State | South Carolina | SEC | Home | W | 82–73 | Regular | Breslin Events Center |
| 162 | 2010-11-22 | 2010–11 | #2 Michigan State | Chaminade | - | Away | W | 82–74 | Regular | Lahaina Civic Center |
| 163 | 2010-11-23 | 2010–11 | #2 Michigan State | Connecticut | Big East | Neutral | L | 67–70 | Regular | Lahaina Civic Center |
| 164 | 2010-11-24 | 2010–11 | #2 Michigan State | #13 Washington | Pacific 10 | Neutral | W | 76–71 | Regular | Lahaina Civic Center |
| 165 | 2010-11-28 | 2010–11 | #2 Michigan State | Tennessee Tech | OVC | Home | W | 73–55 | Regular | Breslin Events Center |
| 166 | 2010-12-01 | 2010–11 | #6 Michigan State | #1 Duke | ACC | Away | L | 79–84 | Regular | Cameron Indoor Stadium |
| 167 | 2010-12-04 | 2010–11 | #6 Michigan State | Bowling Green | MAC | Home | W | 74–39 | Regular | Breslin Events Center |
| 168 | 2010-12-07 | 2010–11 | #7 Michigan State | #8 Syracuse | Big East | Neutral | L | 58–72 | Regular | Madison Square Garden |
| 169 | 2010-12-11 | 2010–11 | #7 Michigan State | Oakland | Summit | Neutral | W | 77–76 | Regular | The Palace of Auburn Hills |
| 170 | 2010-12-18 | 2010–11 | #14 Michigan State | Prairie View | SWAC | Home | W | 90–51 | Regular | Breslin Events Center |
| 171 | 2010-12-22 | 2010–11 | #12 Michigan State | #18 Texas | B12 | Home | L | 55–67 | Regular | Breslin Events Center |
| 172 | 2011-03-17 | 2010–11 | #25 Michigan State | UCLA | Pacific 10 | Neutral | L | 76–78 | NCAA | Benchmark International Arena |
| 173 | 2011-11-11 | 2011–12 | Michigan State | #1 North Carolina | ACC | Neutral | L | 55–67 | Regular | USS Carl Vinson |
| 174 | 2011-11-15 | 2011–12 | Michigan State | #6 Duke | ACC | Neutral | L | 69–74 | Regular | Madison Square Garden |
| 175 | 2011-11-18 | 2011–12 | Michigan State | Texas Southern | SWAC | Home | W | 76–41 | Regular | Breslin Events Center |
| 176 | 2011-11-20 | 2011–12 | Michigan State | Little Rock | Sun Belt | Home | W | 69–47 | Regular | Breslin Events Center |
| 177 | 2011-11-23 | 2011–12 | Michigan State | Milwaukee | Horizon | Home | W | 68–55 | Regular | Breslin Events Center |
| 178 | 2011-11-27 | 2011–12 | Michigan State | Eastern Michigan | MAC | Away | W | 72–40 | Regular | Emil and Patricia Jones Convocation Center |
| 179 | 2011-11-30 | 2011–12 | Michigan State | Florida State | ACC | Home | W | 65–49 | Regular | Breslin Events Center |
| 180 | 2011-12-04 | 2011–12 | Michigan State | Omaha | - | Home | W | 110–68 | Regular | Breslin Events Center |
| 181 | 2011-12-07 | 2011–12 | Michigan State | Central Connecticut State | NEC | Home | W | 89–69 | Regular | Breslin Events Center |
| 182 | 2011-12-10 | 2011–12 | Michigan State | #23 Gonzaga | WCC | Away | W | 74–67 | Regular | McCarthey Athletic Center |
| 183 | 2011-12-17 | 2011–12 | #21 Michigan State | Bowling Green | MAC | Home | W | 74–60 | Regular | Breslin Events Center |
| 184 | 2011-12-19 | 2011–12 | #19 Michigan State | Kansas City | Summit | Home | W | 89–54 | Regular | Breslin Events Center |
| 185 | 2011-12-22 | 2011–12 | #19 Michigan State | Lehigh | Patriot | Home | W | 90–81 | Regular | Breslin Events Center |
| 186 | 2012-03-16 | 2011–12 | #5 Michigan State | Long Island University | NEC | Neutral | W | 89–67 | NCAA | Nationwide Arena |
| 187 | 2012-03-18 | 2011–12 | #5 Michigan State | Saint Louis | A10 | Neutral | W | 65–61 | NCAA | Nationwide Arena |
| 188 | 2012-03-22 | 2011–12 | #5 Michigan State | #17 Louisville | Big East | Neutral | L | 44–57 | NCAA | Mortgage Matchup Center |
| 189 | 2012-11-09 | 2012–13 | #14 Michigan State | Connecticut | Big East | Neutral | L | 62–66 | Regular | Harry A. Gampel Pavilion |
| 190 | 2012-11-13 | 2012–13 | #21 Michigan State | #7 Kansas | B12 | Neutral | W | 67–64 | Regular | Georgia Dome |
| 191 | 2012-11-18 | 2012–13 | #21 Michigan State | Texas Southern | SWAC | Home | W | 69–41 | Regular | Breslin Events Center |
| 192 | 2012-11-20 | 2012–13 | #15 Michigan State | Boise State | Mountain West | Home | W | 74–70 | Regular | Breslin Events Center |
| 193 | 2012-11-23 | 2012–13 | #15 Michigan State | Oakland | Summit | Home | W | 70–52 | Regular | Breslin Events Center |
| 194 | 2012-11-25 | 2012–13 | #15 Michigan State | Louisiana | Sun Belt | Home | W | 63–60 | Regular | Breslin Events Center |
| 195 | 2012-11-28 | 2012–13 | #13 Michigan State | Miami (FL) | ACC | Away | L | 59–67 | Regular | Watsco Center |
| 196 | 2012-12-01 | 2012–13 | #13 Michigan State | Nicholls State | Southland | Home | W | 84–39 | Regular | Breslin Events Center |
| 197 | 2012-12-05 | 2012–13 | #19 Michigan State | Arkansas-Pine Bluff | SWAC | Home | W | 76–44 | Regular | Breslin Events Center |
| 198 | 2012-12-08 | 2012–13 | #19 Michigan State | Loyola (IL) | Horizon | Home | W | 73–61 | Regular | Breslin Events Center |
| 199 | 2012-12-15 | 2012–13 | #19 Michigan State | Tuskegee | - | Home | W | 92–56 | Regular | Breslin Events Center |
| 200 | 2012-12-18 | 2012–13 | #20 Michigan State | Bowling Green | MAC | Away | W | 64–53 | Regular | Stroh Center |
| 201 | 2012-12-22 | 2012–13 | #20 Michigan State | Texas | B12 | Home | W | 67–56 | Regular | Breslin Events Center |
| 202 | 2013-03-21 | 2012–13 | #9 Michigan State | Valparaiso | Horizon | Neutral | W | 65–54 | NCAA | The Palace of Auburn Hills |
| 203 | 2013-03-23 | 2012–13 | #9 Michigan State | #19 Memphis | CUSA | Neutral | W | 70–48 | NCAA | The Palace of Auburn Hills |
| 204 | 2013-03-29 | 2012–13 | #9 Michigan State | #6 Duke | ACC | Neutral | L | 61–71 | NCAA | Lucas Oil Stadium |
| 205 | 2013-11-08 | 2013–14 | #2 Michigan State | McNeese State | Southland | Home | W | 98–56 | Regular | Breslin Events Center |
| 206 | 2013-11-12 | 2013–14 | #2 Michigan State | #1 Kentucky | SEC | Neutral | W | 78–74 | Regular | United Center |
| 207 | 2013-11-15 | 2013–14 | #2 Michigan State | Columbia | Ivy | Home | W | 62–53 | Regular | Breslin Events Center |
| 208 | 2013-11-18 | 2013–14 | #1 Michigan State | Portland | WCC | Home | W | 82–67 | Regular | Breslin Events Center |
| 209 | 2013-11-22 | 2013–14 | #1 Michigan State | Virginia Tech | ACC | Neutral | W | 96–77 | Regular | Barclays Center |
| 210 | 2013-11-23 | 2013–14 | #1 Michigan State | Oklahoma | B12 | Neutral | W | 87–76 | Regular | Barclays Center |
| 211 | 2013-11-29 | 2013–14 | #1 Michigan State | Mount St. Mary's | NEC | Home | W | 98–65 | Regular | Breslin Events Center |
| 212 | 2013-12-04 | 2013–14 | #1 Michigan State | North Carolina | ACC | Home | L | 65–79 | Regular | Breslin Events Center |
| 213 | 2013-12-14 | 2013–14 | #5 Michigan State | Oakland | Horizon | Neutral | W | 67–63 | Regular | The Palace of Auburn Hills |
| 214 | 2013-12-17 | 2013–14 | #5 Michigan State | North Florida | ASUN | Home | W | 78–48 | Regular | Breslin Events Center |
| 215 | 2013-12-21 | 2013–14 | #5 Michigan State | Texas | B12 | Away | W | 92–78 | Regular | Frank Erwin Center |
| 216 | 2013-12-28 | 2013–14 | #5 Michigan State | New Orleans | Southland | Home | W | 101–48 | Regular | Breslin Events Center |
| 217 | 2014-02-01 | 2013–14 | #7 Michigan State | Georgetown | Big East | Neutral | L | 60–64 | Regular | Madison Square Garden |
| 218 | 2014-03-20 | 2013–14 | #11 Michigan State | Delaware | Colonial | Neutral | W | 93–78 | NCAA | Spokane Arena |
| 219 | 2014-03-22 | 2013–14 | #11 Michigan State | Harvard | Ivy | Neutral | W | 80–73 | NCAA | Spokane Arena |
| 220 | 2014-03-28 | 2013–14 | #11 Michigan State | #3 Virginia | ACC | Neutral | W | 61–59 | NCAA | Madison Square Garden |
| 221 | 2014-03-30 | 2013–14 | #11 Michigan State | #18 Connecticut | AAC | Neutral | L | 54–60 | NCAA | Madison Square Garden |
| 222 | 2014-11-14 | 2014–15 | #18 Michigan State | Navy | Patriot | Away | W | 64–59 | Regular | Alumni Hall |
| 223 | 2014-11-18 | 2014–15 | #19 Michigan State | #4 Duke | ACC | Neutral | L | 71–81 | Regular | Gainbridge Fieldhouse |
| 224 | 2014-11-21 | 2014–15 | #19 Michigan State | Loyola (IL) | Missouri Valley | Home | W | 87–52 | Regular | Breslin Events Center |
| 225 | 2014-11-24 | 2014–15 | #20 Michigan State | Santa Clara | WCC | Home | W | 79–52 | Regular | Breslin Events Center |
| 226 | 2014-11-27 | 2014–15 | #20 Michigan State | Rider | MAAC | Neutral | W | 77–45 | Regular | State Farm Field House |
| 227 | 2014-11-28 | 2014–15 | #20 Michigan State | Marquette | Big East | Neutral | W | 79–68 | Regular | State Farm Field House |
| 228 | 2014-11-30 | 2014–15 | #20 Michigan State | #11 Kansas | B12 | Neutral | L | 56–61 | Regular | State Farm Field House |
| 229 | 2014-12-03 | 2014–15 | #19 Michigan State | Notre Dame | ACC | Away | L | 78–79 OT | Regular | Purcell Pavilion |
| 230 | 2014-12-06 | 2014–15 | #19 Michigan State | Arkansas-Pine Bluff | SWAC | Home | W | 85–52 | Regular | Breslin Events Center |
| 231 | 2014-12-14 | 2014–15 | #19 Michigan State | Oakland | Horizon | Home | W | 87–61 | Regular | Breslin Events Center |
| 232 | 2014-12-17 | 2014–15 | #25 Michigan State | Eastern Michigan | MAC | Home | W | 66–46 | Regular | Breslin Events Center |
| 233 | 2014-12-20 | 2014–15 | #25 Michigan State | Texas Southern | SWAC | Home | L | 64–71 OT | Regular | Breslin Events Center |
| 234 | 2014-12-22 | 2014–15 | #25 Michigan State | The Citadel | SoCon | Home | W | 82–56 | Regular | Breslin Events Center |
| 235 | 2015-03-20 | 2014–15 | #23 Michigan State | Georgia | SEC | Neutral | W | 70–63 | NCAA | Spectrum Center |
| 236 | 2015-03-22 | 2014–15 | #23 Michigan State | #6 Virginia | ACC | Neutral | W | 60–54 | NCAA | Spectrum Center |
| 237 | 2015-03-27 | 2014–15 | #23 Michigan State | #13 Oklahoma | B12 | Neutral | W | 62–58 | NCAA | Carrier Dome |
| 238 | 2015-03-29 | 2014–15 | #23 Michigan State | #17 Louisville | ACC | Neutral | W | 76–70 OT | NCAA | Carrier Dome |
| 239 | 2015-04-04 | 2014–15 | #23 Michigan State | #4 Duke | ACC | Neutral | L | 61–81 | NCAA | Lucas Oil Stadium |
| 240 | 2015-11-13 | 2015–16 | #13 Michigan State | Florida Atlantic | CUSA | Home | W | 82–55 | Regular | Breslin Events Center |
| 241 | 2015-11-17 | 2015–16 | #13 Michigan State | #4 Kansas | B12 | Neutral | W | 79–73 | Regular | United Center |
| 242 | 2015-11-20 | 2015–16 | #13 Michigan State | Arkansas-Pine Bluff | SWAC | Home | W | 92–46 | Regular | Breslin Events Center |
| 243 | 2015-11-23 | 2015–16 | #3 Michigan State | Eastern Michigan | MAC | Home | W | 89–65 | Regular | Breslin Events Center |
| 244 | 2015-11-26 | 2015–16 | #3 Michigan State | Boston College | ACC | Neutral | W | 99–68 | Regular | Titan Gym |
| 245 | 2015-11-27 | 2015–16 | #3 Michigan State | Boise State | Mountain West | Neutral | W | 77–67 | Regular | Titan Gym |
| 246 | 2015-11-29 | 2015–16 | #3 Michigan State | Providence | Big East | Neutral | W | 77–64 | Regular | Honda Center |
| 247 | 2015-12-02 | 2015–16 | #3 Michigan State | #24 Louisville | ACC | Home | W | 71–67 | Regular | Breslin Events Center |
| 248 | 2015-12-05 | 2015–16 | #3 Michigan State | Binghamton | Am. East | Home | W | 76–33 | Regular | Breslin Events Center |
| 249 | 2015-12-09 | 2015–16 | #1 Michigan State | Maryland-Eastern Shore | MEAC | Home | W | 78–35 | Regular | Breslin Events Center |
| 250 | 2015-12-12 | 2015–16 | #1 Michigan State | Florida | SEC | Home | W | 58–52 | Regular | Breslin Events Center |
| 251 | 2015-12-19 | 2015–16 | #1 Michigan State | Northeastern | Colonial | Away | W | 78–58 | Regular | Matthews Arena |
| 252 | 2015-12-22 | 2015–16 | #1 Michigan State | Oakland | Horizon | Neutral | W | 99–93 OT | Regular | The Palace of Auburn Hills |
| 253 | 2016-03-18 | 2015–16 | #2 Michigan State | Middle Tennessee | CUSA | Neutral | L | 81–90 | NCAA | Enterprise Center |
| 254 | 2016-11-11 | 2016–17 | #12 Michigan State | #10 Arizona Wildcats | Pacific 12 | Neutral | L | 63–65 | Regular | Stan Sheriff Center |
| 255 | 2016-11-15 | 2016–17 | #13 Michigan State | #2 Kentucky | SEC | Neutral | L | 48–69 | Regular | Madison Square Garden |
| 256 | 2016-11-18 | 2016–17 | #13 Michigan State | Mississippi Valley State | SWAC | Home | W | 100–53 | Regular | Breslin Events Center |
| 257 | 2016-11-20 | 2016–17 | #13 Michigan State | Florida Gulf Coast | ASUN | Home | W | 78–77 | Regular | Breslin Events Center |
| 258 | 2016-11-23 | 2016–17 | #24 Michigan State | St. John's (NY) | Big East | Neutral | W | 73–62 | Regular | Imperial Arena |
| 259 | 2016-11-24 | 2016–17 | #24 Michigan State | #20 Baylor | B12 | Neutral | L | 58–73 | Regular | Imperial Arena |
| 260 | 2016-11-25 | 2016–17 | #24 Michigan State | Wichita State | Missouri Valley | Neutral | W | 77–72 | Regular | Imperial Arena |
| 261 | 2016-11-29 | 2016–17 | #24 Michigan State | #5 Duke | ACC | Away | L | 69–78 | Regular | Cameron Indoor Stadium |
| 262 | 2016-12-03 | 2016–17 | #24 Michigan State | Oral Roberts | Summit | Home | W | 80–76 | Regular | Breslin Events Center |
| 263 | 2016-12-06 | 2016–17 | #24 Michigan State | Youngstown State | Horizon | Home | W | 77–57 | Regular | Breslin Events Center |
| 264 | 2016-12-10 | 2016–17 | #24 Michigan State | Tennessee Tech | OVC | Home | W | 71–63 | Regular | Breslin Events Center |
| 265 | 2016-12-18 | 2016–17 | #24 Michigan State | Northeastern | Colonial | Home | L | 73–81 | Regular | Breslin Events Center |
| 266 | 2016-12-21 | 2016–17 | #24 Michigan State | Oakland | Horizon | Home | W | 77–65 | Regular | Breslin Events Center |
| 267 | 2017-03-17 | 2016–17 | #24 Michigan State | Miami (FL) | ACC | Neutral | W | 78–58 | NCAA | BOK Center |
| 268 | 2017-03-19 | 2016–17 | #24 Michigan State | #3 Kansas | B12 | Neutral | L | 70–90 | NCAA | BOK Center |
| 269 | 2017-11-10 | 2017–18 | #2 Michigan State | North Florida | ASUN | Home | W | 98–66 | Regular | Breslin Events Center |
| 270 | 2017-11-14 | 2017–18 | #2 Michigan State | #1 Duke | ACC | Neutral | L | 81–88 | Regular | United Center |
| 271 | 2017-11-19 | 2017–18 | #2 Michigan State | Stony Brook | Am. East | Home | W | 93–71 | Regular | Breslin Events Center |
| 272 | 2017-11-23 | 2017–18 | #4 Michigan State | DePaul | Big East | Neutral | W | 73–51 | Regular | Moda Center |
| 273 | 2017-11-25 | 2017–18 | #4 Michigan State | Connecticut | AAC | Neutral | W | 77–57 | Regular | Veterans Memorial Coliseum |
| 274 | 2017-11-26 | 2017–18 | #4 Michigan State | #9 North Carolina | ACC | Neutral | W | 63–45 | Regular | Moda Center |
| 275 | 2017-11-30 | 2017–18 | #3 Michigan State | #5 Notre Dame | ACC | Home | W | 81–63 | Regular | Breslin Events Center |
| 276 | 2017-12-09 | 2017–18 | #3 Michigan State | Southern Utah | Big Sky | Home | W | 88–63 | Regular | Breslin Events Center |
| 277 | 2017-12-16 | 2017–18 | #2 Michigan State | Oakland | Horizon | Neutral | W | 86–73 | Regular | Little Caesars Arena |
| 278 | 2017-12-18 | 2017–18 | #2 Michigan State | Houston Christian | Southland | Home | W | 107–62 | Regular | Breslin Events Center |
| 279 | 2017-12-21 | 2017–18 | #2 Michigan State | Long Beach State | Big West | Home | W | 102–60 | Regular | Breslin Events Center |
| 280 | 2017-12-29 | 2017–18 | #2 Michigan State | Cleveland State | Horizon | Home | W | 111–61 | Regular | Breslin Events Center |
| 281 | 2017-12-31 | 2017–18 | #2 Michigan State | Savannah State | MEAC | Home | W | 108–52 | Regular | Breslin Events Center |
| 282 | 2018-03-16 | 2017–18 | #5 Michigan State | Bucknell | Patriot | Neutral | W | 82–78 | NCAA | Little Caesars Arena |
| 283 | 2018-03-18 | 2017–18 | #5 Michigan State | Syracuse | ACC | Neutral | L | 53–55 | NCAA | Little Caesars Arena |
| 284 | 2018-11-06 | 2018–19 | #10 Michigan State | #1 Kansas | B12 | Neutral | L | 87–92 | Regular | Gainbridge Fieldhouse |
| 285 | 2018-11-11 | 2018–19 | #10 Michigan State | Florida Gulf Coast | ASUN | Home | W | 106–82 | Regular | Breslin Events Center |
| 286 | 2018-11-14 | 2018–19 | #11 Michigan State | Louisiana-Monroe | Sun Belt | Home | W | 80–59 | Regular | Breslin Events Center |
| 287 | 2018-11-18 | 2018–19 | #11 Michigan State | Tennessee Tech | OVC | Home | W | 101–33 | Regular | Breslin Events Center |
| 288 | 2018-11-22 | 2018–19 | #11 Michigan State | #17 UCLA | Pacific 12 | Neutral | W | 87–67 | Regular | Orleans Arena |
| 289 | 2018-11-23 | 2018–19 | #11 Michigan State | Texas | B12 | Neutral | W | 78–68 | Regular | Orleans Arena |
| 290 | 2018-11-27 | 2018–19 | #9 Michigan State | Louisville | ACC | Away | L | 78–82 OT | Regular | KFC Yum! Center |
| 291 | 2018-12-08 | 2018–19 | #10 Michigan State | Florida | SEC | Away | W | 63–59 | Regular | Stephen C. O'Connell Center |
| 292 | 2018-12-16 | 2018–19 | #9 Michigan State | Green Bay | Horizon | Home | W | 104–83 | Regular | Breslin Events Center |
| 293 | 2018-12-21 | 2018–19 | #10 Michigan State | Oakland | Horizon | Home | W | 99–69 | Regular | Breslin Events Center |
| 294 | 2018-12-29 | 2018–19 | #8 Michigan State | Northern Illinois | MAC | Home | W | 88–60 | Regular | Breslin Events Center |
| 295 | 2019-03-21 | 2018–19 | #5 Michigan State | Bradley | Missouri Valley | Neutral | W | 76–65 | NCAA | Wells Fargo Arena |
| 296 | 2019-03-29 | 2018–19 | #5 Michigan State | #12 Louisiana State | SEC | Neutral | W | 80–63 | NCAA | Capital One Arena |
| 297 | 2019-03-31 | 2018–19 | #5 Michigan State | #1 Duke | ACC | Neutral | W | 68–67 | NCAA | Capital One Arena |
| 298 | 2019-04-06 | 2018–19 | #5 Michigan State | #9 Texas Tech | B12 | Neutral | L | 51–61 | NCAA | U.S. Bank Stadium |
| 299 | 2019-11-05 | 2019–20 | #1 Michigan State | #2 Kentucky | SEC | Neutral | L | 62–69 | Regular | Madison Square Garden |
| 300 | 2019-11-10 | 2019–20 | #1 Michigan State | Binghamton | Am. East | Home | W | 100–47 | Regular | Breslin Events Center |
| 301 | 2019-11-14 | 2019–20 | #3 Michigan State | #12 Seton Hall | Big East | Away | W | 76–73 | Regular | Prudential Center |
| 302 | 2019-11-18 | 2019–20 | #3 Michigan State | Charleston Southern | Big South | Home | W | 94–46 | Regular | Breslin Events Center |
| 303 | 2019-11-25 | 2019–20 | #3 Michigan State | Virginia Tech | ACC | Neutral | L | 66–71 | Regular | Lahaina Civic Center |
| 304 | 2019-11-26 | 2019–20 | #3 Michigan State | Georgia | SEC | Neutral | W | 93–85 | Regular | Lahaina Civic Center |
| 305 | 2019-11-27 | 2019–20 | #3 Michigan State | UCLA | Pacific 12 | Neutral | W | 75–62 | Regular | Lahaina Civic Center |
| 306 | 2019-12-03 | 2019–20 | #11 Michigan State | #10 Duke | ACC | Home | L | 75–87 | Regular | Breslin Events Center |
| 307 | 2019-12-14 | 2019–20 | #16 Michigan State | Oakland | Horizon | Neutral | W | 72–49 | Regular | Little Caesars Arena |
| 308 | 2019-12-21 | 2019–20 | #15 Michigan State | Eastern Michigan | MAC | Home | W | 101–48 | Regular | Breslin Events Center |
| 309 | 2019-12-29 | 2019–20 | #14 Michigan State | Western Michigan | MAC | Home | W | 95–62 | Regular | Breslin Events Center |
| 310 | 2020-11-25 | 2020–21 | #13 Michigan State | Eastern Michigan | MAC | Home | W | 83–67 | Regular | Breslin Events Center |
| 311 | 2020-11-28 | 2020–21 | #13 Michigan State | Notre Dame | ACC | Home | W | 80–70 | Regular | Breslin Events Center |
| 312 | 2020-12-01 | 2020–21 | #8 Michigan State | #6 Duke | ACC | Away | W | 75–69 | Regular | Cameron Indoor Stadium |
| 313 | 2020-12-04 | 2020–21 | #8 Michigan State | Detroit Mercy | Horizon | Home | W | 83–76 | Regular | Breslin Events Center |
| 314 | 2020-12-06 | 2020–21 | #8 Michigan State | Western Michigan | MAC | Home | W | 79–61 | Regular | Breslin Events Center |
| 315 | 2020-12-13 | 2020–21 | #4 Michigan State | Oakland | Horizon | Home | W | 109–91 | Regular | Breslin Events Center |
| 316 | 2021-03-18 | 2020–21 | #23 Michigan State | UCLA | Pacific 12 | Neutral | L | 80–86 OT | NCAA | Mackey Arena |
| 317 | 2021-11-09 | 2021–22 | Michigan State | #3 Kansas | B12 | Neutral | L | 74–87 | Regular | Madison Square Garden |
| 318 | 2021-11-12 | 2021–22 | Michigan State | Western Michigan | MAC | Home | W | 90–46 | Regular | Breslin Events Center |
| 319 | 2021-11-17 | 2021–22 | Michigan State | Butler | Big East | Away | W | 73–52 | Regular | Hinkle Fieldhouse |
| 320 | 2021-11-20 | 2021–22 | Michigan State | Eastern Michigan | MAC | Home | W | 83–59 | Regular | Breslin Events Center |
| 321 | 2021-11-24 | 2021–22 | Michigan State | Loyola (IL) | Missouri Valley | Neutral | W | 63–61 | Regular | Imperial Arena |
| 322 | 2021-11-25 | 2021–22 | Michigan State | #22 Connecticut | Big East | Neutral | W | 64–60 | Regular | Imperial Arena |
| 323 | 2021-11-26 | 2021–22 | Michigan State | #6 Baylor | B12 | Neutral | L | 58–75 | Regular | Imperial Arena |
| 324 | 2021-12-01 | 2021–22 | #22 Michigan State | Louisville | ACC | Home | W | 73–64 | Regular | Breslin Events Center |
| 325 | 2021-12-04 | 2021–22 | #22 Michigan State | Toledo | MAC | Home | W | 81–68 | Regular | Breslin Events Center |
| 326 | 2021-12-21 | 2021–22 | #11 Michigan State | Oakland | Horizon | Neutral | W | 90–78 | Regular | Little Caesars Arena |
| 327 | 2021-12-29 | 2021–22 | #10 Michigan State | High Point | Big South | Home | W | 81–68 | Regular | Breslin Events Center |
| 328 | 2022-03-18 | 2021–22 | #19 Michigan State | Davidson | A10 | Neutral | W | 74–73 | NCAA | Bon Secours Wellness Arena |
| 329 | 2022-03-20 | 2021–22 | #19 Michigan State | #9 Duke | ACC | Neutral | L | 76–85 | NCAA | Bon Secours Wellness Arena |
| 330 | 2022-11-07 | 2022–23 | Michigan State | Northern Arizona | Big Sky | Home | W | 73–55 | Regular | Breslin Events Center |
| 331 | 2022-11-11 | 2022–23 | Michigan State | #2 Gonzaga | WCC | Neutral | L | 63–64 | Regular | USS Abraham Lincoln |
| 332 | 2022-11-15 | 2022–23 | Michigan State | #4 Kentucky | SEC | Neutral | W | 86–77 2OT | Regular | Gainbridge Fieldhouse |
| 333 | 2022-11-18 | 2022–23 | Michigan State | Villanova | Big East | Home | W | 73–71 | Regular | Breslin Events Center |
| 334 | 2022-11-24 | 2022–23 | #12 Michigan State | #18 Alabama | SEC | Neutral | L | 70–81 | Regular | Moda Center |
| 335 | 2022-11-26 | 2022–23 | #12 Michigan State | Oregon | Pacific 12 | Neutral | W | 74–70 | Regular | Veterans Memorial Coliseum |
| 336 | 2022-11-27 | 2022–23 | #12 Michigan State | Portland | WCC | Away | W | 78–77 | Regular | Chiles Center |
| 337 | 2022-11-30 | 2022–23 | #20 Michigan State | Notre Dame | ACC | Away | L | 52–70 | Regular | Purcell Pavilion |
| 338 | 2022-12-10 | 2022–23 | #20 Michigan State | Brown | Ivy | Home | W | 68–50 | Regular | Breslin Events Center |
| 339 | 2022-12-21 | 2022–23 | #20 Michigan State | Oakland | Horizon | Home | W | 67–54 | Regular | Breslin Events Center |
| 340 | 2022-12-30 | 2022–23 | #20 Michigan State | Buffalo | MAC | Home | W | 89–68 | Regular | Breslin Events Center |
| 341 | 2023-03-17 | 2022–23 | #20 Michigan State | Southern California | Pacific 12 | Neutral | W | 72–62 | NCAA | Nationwide Arena |
| 342 | 2023-03-19 | 2022–23 | #20 Michigan State | #6 Marquette | Big East | Neutral | W | 69–60 | NCAA | Nationwide Arena |
| 343 | 2023-03-23 | 2022–23 | #20 Michigan State | #15 Kansas State | B12 | Neutral | L | 93–98 OT | NCAA | Madison Square Garden |
| 344 | 2023-11-06 | 2023–24 | #4 Michigan State | James Madison | Sun Belt | Home | L | 76–79 OT | Regular | Breslin Events Center |
| 345 | 2023-11-09 | 2023–24 | #4 Michigan State | Southern Indiana | OVC | Home | W | 74–51 | Regular | Breslin Events Center |
| 346 | 2023-11-14 | 2023–24 | #18 Michigan State | #9 Duke | ACC | Neutral | L | 65–74 | Regular | United Center |
| 347 | 2023-11-17 | 2023–24 | #18 Michigan State | Butler | Big East | Home | W | 74–54 | Regular | Breslin Events Center |
| 348 | 2023-11-19 | 2023–24 | #18 Michigan State | Alcorn State | SWAC | Home | W | 81–49 | Regular | Breslin Events Center |
| 349 | 2023-11-23 | 2023–24 | #21 Michigan State | #3 Arizona Wildcats | Pacific 12 | Neutral | L | 68–74 | Regular | Acrisure Arena |
| 350 | 2023-11-28 | 2023–24 | #21 Michigan State | Georgia Southern | Sun Belt | Home | W | 86–55 | Regular | Breslin Events Center |
| 351 | 2023-12-16 | 2023–24 | #21 Michigan State | #6 Baylor | B12 | Neutral | W | 88–64 | Regular | Little Caesars Arena |
| 352 | 2023-12-18 | 2023–24 | #21 Michigan State | Oakland | Horizon | Home | W | 79–62 | Regular | Breslin Events Center |
| 353 | 2023-12-21 | 2023–24 | #21 Michigan State | Stony Brook | Coastal | Home | W | 99–55 | Regular | Breslin Events Center |
| 354 | 2023-12-30 | 2023–24 | #21 Michigan State | Indiana State | Missouri Valley | Home | W | 87–75 | Regular | Breslin Events Center |
| 355 | 2024-03-21 | 2023–24 | #21 Michigan State | Mississippi State | SEC | Neutral | W | 69–51 | NCAA | Spectrum Center |
| 356 | 2024-03-23 | 2023–24 | #21 Michigan State | #5 North Carolina | ACC | Neutral | L | 69–85 | NCAA | Spectrum Center |
| 357 | 2024-11-04 | 2024–25 | Michigan State | Monmouth | Coastal | Home | W | 81–57 | Regular | Breslin Events Center |
| 358 | 2024-11-07 | 2024–25 | Michigan State | Niagara | MAAC | Home | W | 96–60 | Regular | Breslin Events Center |
| 359 | 2024-11-12 | 2024–25 | Michigan State | #1 Kansas | B12 | Neutral | L | 69–77 | Regular | State Farm Arena |
| 360 | 2024-11-16 | 2024–25 | Michigan State | Bowling Green | MAC | Home | W | 86–72 | Regular | Breslin Events Center |
| 361 | 2024-11-19 | 2024–25 | Michigan State | Samford | SoCon | Home | W | 83–75 | Regular | Breslin Events Center |
| 362 | 2024-11-25 | 2024–25 | Michigan State | Colorado | B12 | Neutral | W | 72–56 | Regular | Lahaina Civic Center |
| 363 | 2024-11-26 | 2024–25 | Michigan State | Memphis | AAC | Neutral | L | 63–71 | Regular | Lahaina Civic Center |
| 364 | 2024-11-27 | 2024–25 | Michigan State | #12 North Carolina | ACC | Neutral | W | 94–91 OT | Regular | Lahaina Civic Center |
| 365 | 2024-12-17 | 2024–25 | #20 Michigan State | Oakland | Horizon | Neutral | W | 77–58 | Regular | Little Caesars Arena |
| 366 | 2024-12-21 | 2024–25 | #20 Michigan State | Florida Atlantic | AAC | Home | W | 86–69 | Regular | Breslin Events Center |
| 367 | 2024-12-30 | 2024–25 | #18 Michigan State | Western Michigan | MAC | Home | W | 80–62 | Regular | Breslin Events Center |
| 368 | 2025-03-21 | 2024–25 | #8 Michigan State | Bryant | Am. East | Neutral | W | 87–62 | NCAA | Rocket Arena |
| 369 | 2025-03-23 | 2024–25 | #8 Michigan State | New Mexico | Mountain West | Neutral | W | 71–63 | NCAA | Rocket Arena |
| 370 | 2025-03-28 | 2024–25 | #8 Michigan State | Mississippi | SEC | Neutral | W | 73–70 | NCAA | State Farm Arena |
| 371 | 2025-03-30 | 2024–25 | #8 Michigan State | #4 Auburn | SEC | Neutral | L | 64–70 | NCAA | State Farm Arena |
| 372 | 2025-11-03 | 2025–26 | #22 Michigan State | Colgate | Patriot | Home | W | 80–69 | Regular | Breslin Events Center |
| 373 | 2025-11-08 | 2025–26 | #22 Michigan State | #14 Arkansas | SEC | Home | W | 69–66 | Regular | Breslin Events Center |
| 374 | 2025-11-13 | 2025–26 | #17 Michigan State | San Jose State | Mountain West | Home | W | 79–60 | Regular | Breslin Events Center |
| 375 | 2025-11-18 | 2025–26 | #17 Michigan State | #12 Kentucky | SEC | Neutral | W | 83–66 | Regular | Madison Square Garden |
| 376 | 2025-11-21 | 2025–26 | #17 Michigan State | Detroit Mercy | Horizon | Home | W | 84–56 | Regular | Breslin Events Center |
| 377 | 2025-11-25 | 2025–26 | #11 Michigan State | East Carolina | American | Neutral | W | 89–56 | Regular | Suncoast Credit Union Arena |
| 378 | 2025-11-27 | 2025–26 | #11 Michigan State | #16 North Carolina | ACC | Neutral | W | 74–58 | Regular | Suncoast Credit Union Arena |
| 379 | 2025-12-06 | 2025–26 | #7 Michigan State | #4 Duke | ACC | Home | L | 60–66 | Regular | Breslin Events Center |
| 380 | 2025-12-16 | 2025–26 | #9 Michigan State | Toledo | MAC | Home | W | 92–69 | Regular | Breslin Events Center |
| 381 | 2025-12-20 | 2025–26 | #9 Michigan State | Oakland | Horizon | Neutral | W | 79–70 | Regular | Little Caesars Arena |
| 382 | 2025-12-29 | 2025–26 | #9 Michigan State | Cornell | Ivy | Home | W | 114–97 | Regular | Breslin Events Center |
| 383 | 2026-03-19 | 2025–26 | #11 Michigan State | North Dakota State | Summit | Neutral | W | 92–67 | NCAA | KeyBank Center |
| 384 | 2026-03-21 | 2025–26 | #11 Michigan State | #23 Louisville | ACC | Neutral | W | 77–69 | NCAA | KeyBank Center |
| 385 | 2026-03-27 | 2025–26 | #11 Michigan State | #7 Connecticut | Big East | Neutral | L | 63–67 | NCAA | Capital One Arena |