Kelvin Sampson — Non-Conference Game Record
at Houston
144–31
82.3%
win rate
+16.6
avg margin
175
games
Games (175)
| # | Date | Season | School | Opponent | Opp. Conf. | Loc | W/L | Score | Type | Arena |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2014-11-14 | 2014–15 | Houston | Murray State | OVC | Away | W | 77–74 | Regular | CFSB Center |
| 2 | 2014-11-22 | 2014–15 | Houston | Morgan State | MEAC | Home | W | 72–57 | Regular | Fertitta Center |
| 3 | 2014-11-25 | 2014–15 | Houston | Harvard | Ivy | Away | L | 63–84 | Regular | Lavietes Pavilion |
| 4 | 2014-12-04 | 2014–15 | Houston | Texas-Rio Grande Valley | WAC | Home | W | 72–58 | Regular | Fertitta Center |
| 5 | 2014-12-06 | 2014–15 | Houston | Abilene Christian | Southland | Home | W | 71–59 | Regular | Fertitta Center |
| 6 | 2014-12-16 | 2014–15 | Houston | Houston Christian | Southland | Home | W | 83–76 | Regular | Fertitta Center |
| 7 | 2014-12-17 | 2014–15 | Houston | Arkansas-Pine Bluff | SWAC | Home | L | 56–61 OT | Regular | Fertitta Center |
| 8 | 2014-12-20 | 2014–15 | Houston | South Carolina State | MEAC | Home | L | 63–71 | Regular | Fertitta Center |
| 9 | 2014-12-22 | 2014–15 | Houston | Boise State | Mountain West | Neutral | L | 73–75 OT | Regular | Orleans Arena |
| 10 | 2014-12-23 | 2014–15 | Houston | Texas Tech | B12 | Neutral | W | 82–69 | Regular | Orleans Arena |
| 11 | 2014-12-28 | 2014–15 | Houston | Mississippi Valley State | SWAC | Home | W | 80–53 | Regular | Fertitta Center |
| 12 | 2015-01-28 | 2014–15 | Houston | Rice | CUSA | Home | W | 59–48 | Regular | Fertitta Center |
| 13 | 2015-11-18 | 2015–16 | Houston | Prairie View | SWAC | Home | W | 110–69 | Regular | Fertitta Center |
| 14 | 2015-11-21 | 2015–16 | Houston | Florida A&M | MEAC | Home | W | 97–52 | Regular | Fertitta Center |
| 15 | 2015-11-28 | 2015–16 | Houston | Louisiana-Monroe | Sun Belt | Home | W | 76–64 | Regular | Fertitta Center |
| 16 | 2015-11-30 | 2015–16 | Houston | Texas-Rio Grande Valley | WAC | Home | W | 78–65 | Regular | Fertitta Center |
| 17 | 2015-12-02 | 2015–16 | Houston | Murray State | OVC | Home | W | 93–78 | Regular | Fertitta Center |
| 18 | 2015-12-08 | 2015–16 | Houston | Rhode Island | A10 | Away | L | 57–67 | Regular | Ryan Center |
| 19 | 2015-12-13 | 2015–16 | Houston | Louisiana State | SEC | Home | W | 105–98 OT | Regular | Fertitta Center |
| 20 | 2015-12-16 | 2015–16 | Houston | North Carolina Central | MEAC | Home | W | 73–65 | Regular | Fertitta Center |
| 21 | 2015-12-19 | 2015–16 | Houston | Eastern Illinois | OVC | Home | W | 81–65 | Regular | Fertitta Center |
| 22 | 2015-12-21 | 2015–16 | Houston | Grand Canyon | WAC | Neutral | L | 69–78 | Regular | Cox Pavilion |
| 23 | 2015-12-22 | 2015–16 | Houston | Wyoming | Mountain West | Neutral | W | 94–89 2OT | Regular | Cox Pavilion |
| 24 | 2015-12-28 | 2015–16 | Houston | Nicholls State | Southland | Home | W | 76–49 | Regular | Fertitta Center |
| 25 | 2016-03-16 | 2015–16 | Houston | Georgia Tech | ACC | Away | L | 62–81 | NIT | McCamish Pavilion |
| 26 | 2016-11-11 | 2016–17 | Houston | Morgan State | MEAC | Home | W | 93–52 | Regular | Fertitta Center |
| 27 | 2016-11-21 | 2016–17 | Houston | George Mason | A10 | Neutral | W | 93–56 | Regular | Hertz Arena |
| 28 | 2016-11-22 | 2016–17 | Houston | South Dakota | Summit | Neutral | W | 85–58 | Regular | Hertz Arena |
| 29 | 2016-11-23 | 2016–17 | Houston | Vermont | Am. East | Neutral | W | 72–71 | Regular | Hertz Arena |
| 30 | 2016-11-26 | 2016–17 | Houston | Cornell | Ivy | Home | W | 83–53 | Regular | Fertitta Center |
| 31 | 2016-11-29 | 2016–17 | Houston | Louisiana State | SEC | Away | L | 65–84 | Regular | Maravich Assembly Center |
| 32 | 2016-12-03 | 2016–17 | Houston | Prairie View | SWAC | Home | W | 105–61 | Regular | Fertitta Center |
| 33 | 2016-12-06 | 2016–17 | Houston | Arkansas | SEC | Away | L | 72–84 | Regular | Bud Walton Arena |
| 34 | 2016-12-10 | 2016–17 | Houston | Rhode Island | A10 | Home | W | 82–77 | Regular | Fertitta Center |
| 35 | 2016-12-17 | 2016–17 | Houston | Texas-Rio Grande Valley | WAC | Home | W | 83–58 | Regular | Fertitta Center |
| 36 | 2016-12-21 | 2016–17 | Houston | Liberty | Big South | Home | W | 77–54 | Regular | Fertitta Center |
| 37 | 2016-12-23 | 2016–17 | Houston | Harvard | Ivy | Home | L | 56–57 | Regular | Fertitta Center |
| 38 | 2017-03-15 | 2016–17 | Houston | Akron | MAC | Neutral | L | 75–78 | NIT | Health & Physical Education Arena |
| 39 | 2017-11-10 | 2017–18 | Houston | McNeese State | Southland | Home | W | 81–53 | Regular | Health & Physical Education Arena |
| 40 | 2017-11-17 | 2017–18 | Houston | Drexel | Colonial | Neutral | L | 80–84 | Regular | Vines Center |
| 41 | 2017-11-18 | 2017–18 | Houston | Liberty | Big South | Neutral | W | 68–66 | Regular | Vines Center |
| 42 | 2017-11-19 | 2017–18 | Houston | Wake Forest | ACC | Neutral | W | 78–73 | Regular | Vines Center |
| 43 | 2017-11-25 | 2017–18 | Houston | Incarnate Word | Southland | Home | W | 97–58 | Regular | Health & Physical Education Arena |
| 44 | 2017-11-29 | 2017–18 | Houston | New Orleans | Southland | Home | W | 75–66 | Regular | Health & Physical Education Arena |
| 45 | 2017-12-02 | 2017–18 | Houston | Arkansas | SEC | Home | W | 91–65 | Regular | Health & Physical Education Arena |
| 46 | 2017-12-06 | 2017–18 | Houston | Fairfield | MAAC | Home | W | 88–66 | Regular | Health & Physical Education Arena |
| 47 | 2017-12-09 | 2017–18 | Houston | Saint Louis | A10 | Away | W | 77–58 | Regular | Chaifetz Arena |
| 48 | 2017-12-13 | 2017–18 | Houston | Louisiana State | SEC | Away | L | 77–80 | Regular | Maravich Assembly Center |
| 49 | 2017-12-17 | 2017–18 | Houston | Prairie View | SWAC | Home | W | 92–72 | Regular | Health & Physical Education Arena |
| 50 | 2017-12-20 | 2017–18 | Houston | Providence | Big East | Neutral | W | 70–59 | Regular | Mohegan Sun Arena |
| 51 | 2018-03-15 | 2017–18 | #21 Houston | San Diego State | Mountain West | Neutral | W | 67–65 | NCAA | Intrust Bank Arena |
| 52 | 2018-03-17 | 2017–18 | #21 Houston | #7 Michigan | B10 | Neutral | L | 63–64 | NCAA | Intrust Bank Arena |
| 53 | 2018-11-10 | 2018–19 | Houston | Alabama A&M | SWAC | Home | W | 101–54 | Regular | Health & Physical Education Arena |
| 54 | 2018-11-14 | 2018–19 | Houston | Rice | CUSA | Home | W | 79–68 | Regular | Health & Physical Education Arena |
| 55 | 2018-11-19 | 2018–19 | Houston | Northwestern State | Southland | Home | W | 82–55 | Regular | Health & Physical Education Arena |
| 56 | 2018-11-24 | 2018–19 | Houston | Brigham Young | WCC | Away | W | 76–62 | Regular | Marriott Center |
| 57 | 2018-11-28 | 2018–19 | Houston | Texas-Rio Grande Valley | WAC | Home | W | 58–53 | Regular | Health & Physical Education Arena |
| 58 | 2018-12-01 | 2018–19 | Houston | #18 Oregon | Pacific 12 | Home | W | 65–61 | Regular | Fertitta Center |
| 59 | 2018-12-04 | 2018–19 | Houston | Lamar | Southland | Home | W | 79–56 | Regular | Fertitta Center |
| 60 | 2018-12-08 | 2018–19 | Houston | Oklahoma State | B12 | Away | W | 63–53 | Regular | Gallagher-Iba Arena |
| 61 | 2018-12-12 | 2018–19 | #24 Houston | Louisiana State | SEC | Home | W | 82–76 | Regular | Fertitta Center |
| 62 | 2018-12-16 | 2018–19 | #24 Houston | Saint Louis | A10 | Home | W | 68–64 | Regular | Fertitta Center |
| 63 | 2018-12-20 | 2018–19 | #21 Houston | Utah State | Mountain West | Home | W | 60–50 | Regular | Fertitta Center |
| 64 | 2018-12-23 | 2018–19 | #21 Houston | Coppin State | MEAC | Home | W | 75–44 | Regular | Fertitta Center |
| 65 | 2018-12-29 | 2018–19 | #22 Houston | NJIT | ASUN | Home | W | 80–59 | Regular | Fertitta Center |
| 66 | 2019-03-22 | 2018–19 | #11 Houston | Georgia State | Sun Belt | Neutral | W | 84–55 | NCAA | BOK Center |
| 67 | 2019-03-24 | 2018–19 | #11 Houston | Ohio State | B10 | Neutral | W | 74–59 | NCAA | BOK Center |
| 68 | 2019-03-29 | 2018–19 | #11 Houston | #7 Kentucky | SEC | Neutral | L | 58–62 | NCAA | T-Mobile Center |
| 69 | 2019-11-12 | 2019–20 | Houston | Alabama State | SWAC | Home | W | 84–56 | Regular | Fertitta Center |
| 70 | 2019-11-15 | 2019–20 | Houston | Brigham Young | WCC | Home | L | 71–72 | Regular | Fertitta Center |
| 71 | 2019-11-19 | 2019–20 | Houston | Rice | CUSA | Away | W | 97–89 | Regular | Tudor Fieldhouse |
| 72 | 2019-11-22 | 2019–20 | Houston | #11 Oregon | Pacific 12 | Away | L | 66–78 | Regular | Matthew Knight Arena |
| 73 | 2019-11-26 | 2019–20 | Houston | Houston Christian | Southland | Home | W | 112–73 | Regular | Fertitta Center |
| 74 | 2019-12-04 | 2019–20 | Houston | Texas State | Sun Belt | Home | W | 68–60 | Regular | Fertitta Center |
| 75 | 2019-12-08 | 2019–20 | Houston | South Carolina | SEC | Away | W | 76–56 | Regular | Colonial Life Arena |
| 76 | 2019-12-11 | 2019–20 | Houston | UT Arlington | Sun Belt | Home | W | 71–63 | Regular | Fertitta Center |
| 77 | 2019-12-15 | 2019–20 | Houston | Oklahoma State | B12 | Home | L | 55–61 | Regular | Fertitta Center |
| 78 | 2019-12-19 | 2019–20 | Houston | UTEP | CUSA | Home | W | 77–57 | Regular | Fertitta Center |
| 79 | 2019-12-22 | 2019–20 | Houston | Portland | WCC | Neutral | W | 81–56 | Regular | Stan Sheriff Center |
| 80 | 2019-12-23 | 2019–20 | Houston | Georgia Tech | ACC | Neutral | W | 70–59 | Regular | Stan Sheriff Center |
| 81 | 2019-12-25 | 2019–20 | Houston | #21 Washington | Pacific 12 | Neutral | W | 75–71 | Regular | Stan Sheriff Center |
| 82 | 2020-11-25 | 2020–21 | #17 Houston | Lamar | Southland | Home | W | 89–45 | Regular | Fertitta Center |
| 83 | 2020-11-27 | 2020–21 | #17 Houston | Boise State | Mountain West | Home | W | 68–58 | Regular | Fertitta Center |
| 84 | 2020-11-29 | 2020–21 | #17 Houston | #14 Texas Tech | B12 | Neutral | W | 64–53 | Regular | Dickies Arena |
| 85 | 2020-12-05 | 2020–21 | #10 Houston | South Carolina | SEC | Home | W | 77–67 | Regular | Fertitta Center |
| 86 | 2020-12-20 | 2020–21 | #6 Houston | Alcorn State | SWAC | Home | W | 88–55 | Regular | Fertitta Center |
| 87 | 2021-02-06 | 2020–21 | #5 Houston | Our Lady of the Lake | - | Home | W | 112–46 | Regular | Fertitta Center |
| 88 | 2021-02-25 | 2020–21 | #12 Houston | Western Kentucky | CUSA | Home | W | 81–57 | Regular | Fertitta Center |
| 89 | 2021-03-19 | 2020–21 | #6 Houston | Cleveland State | Horizon | Neutral | W | 87–56 | NCAA | Simon Skjodt Assembly Hall |
| 90 | 2021-03-21 | 2020–21 | #6 Houston | Rutgers | B10 | Neutral | W | 63–60 | NCAA | Lucas Oil Stadium |
| 91 | 2021-03-27 | 2020–21 | #6 Houston | Syracuse | ACC | Neutral | W | 62–46 | NCAA | Hinkle Fieldhouse |
| 92 | 2021-03-29 | 2020–21 | #6 Houston | Oregon State | Pacific 12 | Neutral | W | 67–61 | NCAA | Lucas Oil Stadium |
| 93 | 2021-04-03 | 2020–21 | #6 Houston | #3 Baylor | B12 | Neutral | L | 59–78 | NCAA | Lucas Oil Stadium |
| 94 | 2021-11-09 | 2021–22 | #15 Houston | Hofstra | Colonial | Home | W | 83–75 OT | Regular | Fertitta Center |
| 95 | 2021-11-12 | 2021–22 | #15 Houston | Rice | CUSA | Home | W | 79–46 | Regular | Fertitta Center |
| 96 | 2021-11-16 | 2021–22 | #15 Houston | Virginia | ACC | Home | W | 67–47 | Regular | Fertitta Center |
| 97 | 2021-11-22 | 2021–22 | #12 Houston | Butler | Big East | Neutral | W | 70–52 | Regular | Michelob Ultra Arena |
| 98 | 2021-11-23 | 2021–22 | #12 Houston | Wisconsin | B10 | Neutral | L | 63–65 | Regular | Michelob Ultra Arena |
| 99 | 2021-11-24 | 2021–22 | #12 Houston | Oregon | Pacific 12 | Neutral | W | 78–49 | Regular | Michelob Ultra Arena |
| 100 | 2021-11-30 | 2021–22 | #15 Houston | Northwestern State | Southland | Home | W | 99–58 | Regular | Fertitta Center |
| 101 | 2021-12-03 | 2021–22 | #15 Houston | Bryant | NEC | Home | W | 111–44 | Regular | Fertitta Center |
| 102 | 2021-12-06 | 2021–22 | #14 Houston | Alcorn State | SWAC | Home | W | 77–45 | Regular | Fertitta Center |
| 103 | 2021-12-11 | 2021–22 | #14 Houston | #9 Alabama | SEC | Away | L | 82–83 | Regular | Coleman Coliseum |
| 104 | 2021-12-14 | 2021–22 | #14 Houston | Louisiana | Sun Belt | Home | W | 71–56 | Regular | Fertitta Center |
| 105 | 2021-12-18 | 2021–22 | #14 Houston | Oklahoma State | B12 | Neutral | W | 72–61 | Regular | Dickies Arena |
| 106 | 2021-12-22 | 2021–22 | #13 Houston | Texas State | Sun Belt | Home | W | 80–47 | Regular | Fertitta Center |
| 107 | 2022-03-18 | 2021–22 | #15 Houston | UAB | CUSA | Neutral | W | 82–68 | NCAA | PPG Paints Arena |
| 108 | 2022-03-20 | 2021–22 | #15 Houston | #19 Illinois | B10 | Neutral | W | 68–53 | NCAA | PPG Paints Arena |
| 109 | 2022-03-24 | 2021–22 | #15 Houston | #2 Arizona Wildcats | Pacific 12 | Neutral | W | 72–60 | NCAA | Frost Bank Center |
| 110 | 2022-03-26 | 2021–22 | #15 Houston | #6 Villanova | Big East | Neutral | L | 44–50 | NCAA | Frost Bank Center |
| 111 | 2022-11-07 | 2022–23 | #3 Houston | Northern Colorado | Big Sky | Home | W | 83–36 | Regular | Fertitta Center |
| 112 | 2022-11-11 | 2022–23 | #3 Houston | Saint Joseph's | A10 | Neutral | W | 81–55 | Regular | Alumni Hall |
| 113 | 2022-11-14 | 2022–23 | #3 Houston | Oral Roberts | Summit | Home | W | 83–45 | Regular | Fertitta Center |
| 114 | 2022-11-16 | 2022–23 | #3 Houston | Texas Southern | SWAC | Home | W | 83–48 | Regular | Fertitta Center |
| 115 | 2022-11-20 | 2022–23 | #3 Houston | Oregon | Pacific 12 | Away | W | 66–56 | Regular | Matthew Knight Arena |
| 116 | 2022-11-26 | 2022–23 | #2 Houston | Kent State | MAC | Home | W | 49–44 | Regular | Fertitta Center |
| 117 | 2022-11-29 | 2022–23 | #1 Houston | Norfolk State | MEAC | Home | W | 100–52 | Regular | Fertitta Center |
| 118 | 2022-12-03 | 2022–23 | #1 Houston | Saint Mary's (CA) | WCC | Neutral | W | 53–48 | Regular | Dickies Arena |
| 119 | 2022-12-06 | 2022–23 | #1 Houston | North Florida | ASUN | Home | W | 76–42 | Regular | Fertitta Center |
| 120 | 2022-12-10 | 2022–23 | #1 Houston | #8 Alabama | SEC | Home | L | 65–71 | Regular | Fertitta Center |
| 121 | 2022-12-13 | 2022–23 | #5 Houston | North Carolina A&T | Colonial | Home | W | 74–46 | Regular | Fertitta Center |
| 122 | 2022-12-17 | 2022–23 | #5 Houston | #2 Virginia | ACC | Away | W | 69–61 | Regular | John Paul Jones Arena |
| 123 | 2022-12-21 | 2022–23 | #3 Houston | McNeese State | Southland | Home | W | 83–44 | Regular | Fertitta Center |
| 124 | 2023-03-16 | 2022–23 | #2 Houston | Northern Kentucky | Horizon | Neutral | W | 63–52 | NCAA | Legacy Arena |
| 125 | 2023-03-18 | 2022–23 | #2 Houston | Auburn | SEC | Neutral | W | 81–64 | NCAA | Legacy Arena |
| 126 | 2023-03-24 | 2022–23 | #2 Houston | #16 Miami (FL) | ACC | Neutral | L | 75–89 | NCAA | T-Mobile Center |
| 127 | 2023-11-06 | 2023–24 | #7 Houston | Louisiana-Monroe | Sun Belt | Home | W | 84–31 | Regular | Fertitta Center |
| 128 | 2023-11-11 | 2023–24 | #7 Houston | Texas A&M-Corpus Christi | Southland | Home | W | 82–50 | Regular | Fertitta Center |
| 129 | 2023-11-13 | 2023–24 | #6 Houston | Stetson | ASUN | Home | W | 79–48 | Regular | Fertitta Center |
| 130 | 2023-11-16 | 2023–24 | #6 Houston | Towson | Coastal | Neutral | W | 65–49 | Regular | TD Arena |
| 131 | 2023-11-17 | 2023–24 | #6 Houston | Utah | Pacific 12 | Neutral | W | 76–66 | Regular | TD Arena |
| 132 | 2023-11-19 | 2023–24 | #6 Houston | Dayton | A10 | Neutral | W | 69–55 | Regular | TD Arena |
| 133 | 2023-11-24 | 2023–24 | #6 Houston | Montana | Big Sky | Home | W | 79–44 | Regular | Fertitta Center |
| 134 | 2023-12-01 | 2023–24 | #6 Houston | Xavier | Big East | Away | W | 66–60 | Regular | Cintas Center |
| 135 | 2023-12-06 | 2023–24 | #3 Houston | Rice | AAC | Home | W | 75–39 | Regular | Fertitta Center |
| 136 | 2023-12-09 | 2023–24 | #3 Houston | Jackson State | SWAC | Home | W | 89–55 | Regular | Fertitta Center |
| 137 | 2023-12-16 | 2023–24 | #4 Houston | Texas A&M | SEC | Neutral | W | 70–66 | Regular | Toyota Center |
| 138 | 2023-12-21 | 2023–24 | #3 Houston | Texas State | Sun Belt | Home | W | 72–37 | Regular | Fertitta Center |
| 139 | 2023-12-30 | 2023–24 | #3 Houston | Pennsylvania | Ivy | Home | W | 81–42 | Regular | Fertitta Center |
| 140 | 2024-03-22 | 2023–24 | #2 Houston | Longwood | Big South | Neutral | W | 86–46 | NCAA | FedExForum |
| 141 | 2024-03-24 | 2023–24 | #2 Houston | Texas A&M | SEC | Neutral | W | 100–95 OT | NCAA | FedExForum |
| 142 | 2024-03-29 | 2023–24 | #2 Houston | #13 Duke | ACC | Neutral | L | 51–54 | NCAA | American Airlines Center |
| 143 | 2024-11-04 | 2024–25 | #4 Houston | Jackson State | SWAC | Home | W | 97–40 | Regular | Fertitta Center |
| 144 | 2024-11-09 | 2024–25 | #4 Houston | #11 Auburn | SEC | Neutral | L | 69–74 | Regular | Toyota Center |
| 145 | 2024-11-13 | 2024–25 | #8 Houston | Louisiana | Sun Belt | Home | W | 91–45 | Regular | Fertitta Center |
| 146 | 2024-11-22 | 2024–25 | #7 Houston | Hofstra | Coastal | Home | W | 80–44 | Regular | Fertitta Center |
| 147 | 2024-11-26 | 2024–25 | #6 Houston | #9 Alabama | SEC | Neutral | L | 80–85 OT | Regular | MGM Grand Garden Arena |
| 148 | 2024-11-28 | 2024–25 | #6 Houston | Notre Dame | ACC | Neutral | W | 65–54 | Regular | MGM Grand Garden Arena |
| 149 | 2024-11-30 | 2024–25 | #6 Houston | San Diego State | Mountain West | Neutral | L | 70–73 OT | Regular | MGM Grand Garden Arena |
| 150 | 2024-12-07 | 2024–25 | #17 Houston | Butler | Big East | Home | W | 79–51 | Regular | Fertitta Center |
| 151 | 2024-12-10 | 2024–25 | #15 Houston | Troy | Sun Belt | Home | W | 62–42 | Regular | Fertitta Center |
| 152 | 2024-12-18 | 2024–25 | #15 Houston | Toledo | MAC | Home | W | 78–49 | Regular | Fertitta Center |
| 153 | 2024-12-21 | 2024–25 | #15 Houston | Texas A&M-Corpus Christi | Southland | Home | W | 87–51 | Regular | Fertitta Center |
| 154 | 2025-03-20 | 2024–25 | #2 Houston | Southern Illinois-Edwardsville | OVC | Neutral | W | 78–40 | NCAA | Intrust Bank Arena |
| 155 | 2025-03-22 | 2024–25 | #2 Houston | #24 Gonzaga | WCC | Neutral | W | 81–76 | NCAA | Intrust Bank Arena |
| 156 | 2025-03-28 | 2024–25 | #2 Houston | #22 Purdue | B10 | Neutral | W | 62–60 | NCAA | Lucas Oil Stadium |
| 157 | 2025-03-30 | 2024–25 | #2 Houston | #6 Tennessee | SEC | Neutral | W | 69–50 | NCAA | Lucas Oil Stadium |
| 158 | 2025-04-05 | 2024–25 | #2 Houston | #1 Duke | ACC | Neutral | W | 70–67 | NCAA | Alamodome |
| 159 | 2025-04-07 | 2024–25 | #2 Houston | #3 Florida | SEC | Neutral | L | 63–65 | NCAA | Alamodome |
| 160 | 2025-11-03 | 2025–26 | #2 Houston | Lehigh | Patriot | Home | W | 75–57 | Regular | Fertitta Center |
| 161 | 2025-11-08 | 2025–26 | #2 Houston | Towson | Coastal | Home | W | 65–48 | Regular | Fertitta Center |
| 162 | 2025-11-12 | 2025–26 | #1 Houston | Oakland | Horizon | Home | W | 78–45 | Regular | Fertitta Center |
| 163 | 2025-11-16 | 2025–26 | #1 Houston | #22 Auburn | SEC | Neutral | W | 73–72 | Regular | Legacy Arena |
| 164 | 2025-11-20 | 2025–26 | #2 Houston | Rider | MAAC | Home | W | 91–45 | Regular | Fertitta Center |
| 165 | 2025-11-24 | 2025–26 | #3 Houston | Syracuse | ACC | Neutral | W | 78–74 OT | Regular | MGM Grand Garden Arena |
| 166 | 2025-11-25 | 2025–26 | #3 Houston | #17 Tennessee | SEC | Neutral | L | 73–76 | Regular | MGM Grand Garden Arena |
| 167 | 2025-11-26 | 2025–26 | #3 Houston | Notre Dame | ACC | Neutral | W | 66–56 | Regular | MGM Grand Garden Arena |
| 168 | 2025-12-06 | 2025–26 | #8 Houston | Florida State | ACC | Neutral | W | 82–67 | Regular | Toyota Center |
| 169 | 2025-12-10 | 2025–26 | #7 Houston | Jackson State | SWAC | Home | W | 80–38 | Regular | Fertitta Center |
| 170 | 2025-12-13 | 2025–26 | #7 Houston | New Orleans | Southland | Home | W | 99–57 | Regular | Fertitta Center |
| 171 | 2025-12-20 | 2025–26 | #8 Houston | #14 Arkansas | SEC | Neutral | W | 94–85 | Regular | Prudential Center |
| 172 | 2025-12-29 | 2025–26 | #8 Houston | Middle Tennessee | CUSA | Home | W | 69–60 | Regular | Fertitta Center |
| 173 | 2026-03-19 | 2025–26 | #5 Houston | Idaho | Big Sky | Neutral | W | 78–47 | NCAA | Paycom Center |
| 174 | 2026-03-21 | 2025–26 | #5 Houston | Texas A&M | SEC | Neutral | W | 88–57 | NCAA | Paycom Center |
| 175 | 2026-03-26 | 2025–26 | #5 Houston | #13 Illinois | B10 | Neutral | L | 55–65 | NCAA | Toyota Center |