Steve Prohm — Regular Season Record
88–88
50.0%
win rate
+2.2
avg margin
176
games
Games (176)
| # | Date | Season | School | Opponent | Opp. Conf. | Loc | W/L | Score | Type | Arena |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-13 | 2015–16 | #7 Iowa State | Colorado | Pacific 12 | Neutral | W | 68–62 | Regular | Sanford Pentagon |
| 2 | 2015-11-16 | 2015–16 | #7 Iowa State | Chicago State | WAC | Home | W | 106–64 | Regular | Hilton Coliseum |
| 3 | 2015-11-23 | 2015–16 | #4 Iowa State | Chattanooga | SoCon | Home | W | 83–63 | Regular | Hilton Coliseum |
| 4 | 2015-11-27 | 2015–16 | #4 Iowa State | Virginia Tech | ACC | Neutral | W | 99–77 | Regular | The Arena at Northwest Florida State College |
| 5 | 2015-11-28 | 2015–16 | #4 Iowa State | Illinois | B10 | Neutral | W | 84–73 | Regular | The Arena at Northwest Florida State College |
| 6 | 2015-12-01 | 2015–16 | #5 Iowa State | North Dakota State | Summit | Home | W | 84–64 | Regular | Hilton Coliseum |
| 7 | 2015-12-07 | 2015–16 | #4 Iowa State | Buffalo | MAC | Home | W | 84–63 | Regular | Hilton Coliseum |
| 8 | 2015-12-10 | 2015–16 | #4 Iowa State | Iowa | B10 | Home | W | 83–82 | Regular | Hilton Coliseum |
| 9 | 2015-12-13 | 2015–16 | #4 Iowa State | Arkansas-Pine Bluff | SWAC | Home | W | 78–64 | Regular | Hilton Coliseum |
| 10 | 2015-12-19 | 2015–16 | #5 Iowa State | Northern Iowa | Missouri Valley | Neutral | L | 79–81 | Regular | Wells Fargo Arena |
| 11 | 2015-12-22 | 2015–16 | #11 Iowa State | #22 Cincinnati | AAC | Away | W | 81–79 | Regular | Fifth Third Arena |
| 12 | 2015-12-30 | 2015–16 | #11 Iowa State | Coppin State | MEAC | Home | W | 104–84 | Regular | Hilton Coliseum |
| 13 | 2016-01-02 | 2015–16 | #11 Iowa State | #3 Oklahoma | B12 | Away | L | 83–87 | Regular | Lloyd Noble Center |
| 14 | 2016-01-06 | 2015–16 | #13 Iowa State | Texas Tech | B12 | Home | W | 76–69 | Regular | Hilton Coliseum |
| 15 | 2016-01-09 | 2015–16 | #13 Iowa State | Baylor | B12 | Home | L | 89–94 | Regular | Hilton Coliseum |
| 16 | 2016-01-12 | 2015–16 | #17 Iowa State | Texas | B12 | Away | L | 91–94 OT | Regular | Frank Erwin Center |
| 17 | 2016-01-16 | 2015–16 | #17 Iowa State | Kansas State | B12 | Away | W | 76–63 | Regular | Bramlage Coliseum |
| 18 | 2016-01-18 | 2015–16 | #19 Iowa State | #1 Oklahoma | B12 | Home | W | 82–77 | Regular | Hilton Coliseum |
| 19 | 2016-01-23 | 2015–16 | #19 Iowa State | TCU | B12 | Away | W | 73–60 | Regular | Schollmaier Arena |
| 20 | 2016-01-25 | 2015–16 | #14 Iowa State | #4 Kansas | B12 | Home | W | 85–72 | Regular | Hilton Coliseum |
| 21 | 2016-01-30 | 2015–16 | #14 Iowa State | #5 Texas A&M | SEC | Away | L | 62–72 | Regular | Reed Arena |
| 22 | 2016-02-02 | 2015–16 | #13 Iowa State | #14 West Virginia | B12 | Home | L | 76–81 | Regular | Hilton Coliseum |
| 23 | 2016-02-06 | 2015–16 | #13 Iowa State | Oklahoma State | B12 | Away | W | 64–59 | Regular | Gallagher-Iba Arena |
| 24 | 2016-02-10 | 2015–16 | #14 Iowa State | Texas Tech | B12 | Away | L | 82–85 OT | Regular | United Supermarkets Arena |
| 25 | 2016-02-13 | 2015–16 | #14 Iowa State | #24 Texas | B12 | Home | W | 85–75 | Regular | Hilton Coliseum |
| 26 | 2016-02-16 | 2015–16 | #13 Iowa State | #25 Baylor | B12 | Away | L | 91–100 OT | Regular | Ferrell Center |
| 27 | 2016-02-20 | 2015–16 | #13 Iowa State | TCU | B12 | Home | W | 92–83 | Regular | Hilton Coliseum |
| 28 | 2016-02-22 | 2015–16 | #17 Iowa State | #14 West Virginia | B12 | Away | L | 87–97 | Regular | Hope Coliseum |
| 29 | 2016-02-27 | 2015–16 | #17 Iowa State | Kansas State | B12 | Home | W | 80–61 | Regular | Hilton Coliseum |
| 30 | 2016-02-29 | 2015–16 | #21 Iowa State | Oklahoma State | B12 | Home | W | 58–50 | Regular | Hilton Coliseum |
| 31 | 2016-03-05 | 2015–16 | #21 Iowa State | #1 Kansas | B12 | Away | L | 78–85 | Regular | Allen Fieldhouse |
| 32 | 2016-11-11 | 2016–17 | #24 Iowa State | Savannah State | MEAC | Home | W | 113–71 | Regular | Hilton Coliseum |
| 33 | 2016-11-14 | 2016–17 | #20 Iowa State | Mount St. Mary's | NEC | Home | W | 73–55 | Regular | Hilton Coliseum |
| 34 | 2016-11-20 | 2016–17 | #20 Iowa State | The Citadel | SoCon | Home | W | 130–63 | Regular | Hilton Coliseum |
| 35 | 2016-11-24 | 2016–17 | #21 Iowa State | Indiana State | Missouri Valley | Neutral | W | 73–71 | Regular | State Farm Field House |
| 36 | 2016-11-25 | 2016–17 | #21 Iowa State | Miami (FL) | ACC | Neutral | W | 73–56 | Regular | State Farm Field House |
| 37 | 2016-11-27 | 2016–17 | #21 Iowa State | #11 Gonzaga | WCC | Neutral | L | 71–73 | Regular | State Farm Field House |
| 38 | 2016-12-01 | 2016–17 | #19 Iowa State | Cincinnati | AAC | Home | L | 54–55 OT | Regular | Hilton Coliseum |
| 39 | 2016-12-05 | 2016–17 | #25 Iowa State | Omaha | Summit | Home | W | 91–47 | Regular | Hilton Coliseum |
| 40 | 2016-12-08 | 2016–17 | #25 Iowa State | Iowa | B10 | Away | L | 64–78 | Regular | Carver-Hawkeye Arena |
| 41 | 2016-12-17 | 2016–17 | #25 Iowa State | Drake | Missouri Valley | Neutral | W | 97–80 | Regular | Wells Fargo Arena |
| 42 | 2016-12-20 | 2016–17 | #25 Iowa State | Mississippi Valley State | SWAC | Home | W | 88–60 | Regular | Hilton Coliseum |
| 43 | 2016-12-30 | 2016–17 | #25 Iowa State | Texas Tech | B12 | Home | W | 63–56 | Regular | Hilton Coliseum |
| 44 | 2017-01-04 | 2016–17 | #25 Iowa State | #2 Baylor | B12 | Away | L | 63–65 | Regular | Ferrell Center |
| 45 | 2017-01-07 | 2016–17 | #25 Iowa State | Texas | B12 | Home | W | 79–70 | Regular | Hilton Coliseum |
| 46 | 2017-01-11 | 2016–17 | #25 Iowa State | Oklahoma State | B12 | Away | W | 96–86 | Regular | Gallagher-Iba Arena |
| 47 | 2017-01-14 | 2016–17 | #25 Iowa State | TCU | B12 | Away | L | 77–84 | Regular | Schollmaier Arena |
| 48 | 2017-01-16 | 2016–17 | #25 Iowa State | #2 Kansas | B12 | Home | L | 72–76 | Regular | Hilton Coliseum |
| 49 | 2017-01-21 | 2016–17 | #25 Iowa State | Oklahoma | B12 | Away | W | 92–87 2OT | Regular | Lloyd Noble Center |
| 50 | 2017-01-24 | 2016–17 | #25 Iowa State | Kansas State | B12 | Home | W | 70–65 | Regular | Hilton Coliseum |
| 51 | 2017-01-28 | 2016–17 | #25 Iowa State | Vanderbilt | SEC | Away | L | 78–84 | Regular | Memorial Gymnasium |
| 52 | 2017-01-31 | 2016–17 | #25 Iowa State | #7 West Virginia | B12 | Home | L | 72–85 | Regular | Hilton Coliseum |
| 53 | 2017-02-04 | 2016–17 | #25 Iowa State | #3 Kansas | B12 | Away | W | 92–89 OT | Regular | Allen Fieldhouse |
| 54 | 2017-02-07 | 2016–17 | #25 Iowa State | Texas | B12 | Away | L | 65–67 | Regular | Frank Erwin Center |
| 55 | 2017-02-11 | 2016–17 | #25 Iowa State | Oklahoma | B12 | Home | W | 80–64 | Regular | Hilton Coliseum |
| 56 | 2017-02-15 | 2016–17 | #25 Iowa State | Kansas State | B12 | Away | W | 87–79 | Regular | Bramlage Coliseum |
| 57 | 2017-02-18 | 2016–17 | #25 Iowa State | TCU | B12 | Home | W | 84–71 | Regular | Hilton Coliseum |
| 58 | 2017-02-20 | 2016–17 | #25 Iowa State | Texas Tech | B12 | Away | W | 82–80 OT | Regular | United Supermarkets Arena |
| 59 | 2017-02-25 | 2016–17 | #25 Iowa State | #9 Baylor | B12 | Home | W | 72–69 | Regular | Hilton Coliseum |
| 60 | 2017-02-28 | 2016–17 | #24 Iowa State | Oklahoma State | B12 | Home | W | 86–83 | Regular | Hilton Coliseum |
| 61 | 2017-03-03 | 2016–17 | #24 Iowa State | #10 West Virginia | B12 | Away | L | 76–87 | Regular | Hope Coliseum |
| 62 | 2017-11-10 | 2017–18 | Iowa State | Missouri | SEC | Away | L | 59–74 | Regular | Mizzou Arena |
| 63 | 2017-11-13 | 2017–18 | Iowa State | Milwaukee | Horizon | Home | L | 56–74 | Regular | Hilton Coliseum |
| 64 | 2017-11-16 | 2017–18 | Iowa State | Appalachian State | Sun Belt | Neutral | W | 104–98 | Regular | HTC Center |
| 65 | 2017-11-17 | 2017–18 | Iowa State | Tulsa | AAC | Neutral | W | 80–78 | Regular | HTC Center |
| 66 | 2017-11-19 | 2017–18 | Iowa State | Boise State | Mountain West | Neutral | W | 75–64 | Regular | HTC Center |
| 67 | 2017-11-25 | 2017–18 | Iowa State | Western Illinois | Summit | Home | W | 70–45 | Regular | Hilton Coliseum |
| 68 | 2017-12-04 | 2017–18 | Iowa State | Northern Illinois | MAC | Home | W | 94–80 | Regular | Hilton Coliseum |
| 69 | 2017-12-07 | 2017–18 | Iowa State | Iowa | B10 | Home | W | 84–78 | Regular | Hilton Coliseum |
| 70 | 2017-12-10 | 2017–18 | Iowa State | Alcorn State | SWAC | Home | W | 78–58 | Regular | Hilton Coliseum |
| 71 | 2017-12-16 | 2017–18 | Iowa State | Northern Iowa | Missouri Valley | Neutral | W | 76–65 | Regular | Wells Fargo Arena |
| 72 | 2017-12-20 | 2017–18 | Iowa State | Maryland-Eastern Shore | MEAC | Home | W | 55–49 | Regular | Hilton Coliseum |
| 73 | 2017-12-29 | 2017–18 | Iowa State | Kansas State | B12 | Home | L | 75–91 | Regular | Hilton Coliseum |
| 74 | 2018-01-01 | 2017–18 | Iowa State | Texas | B12 | Home | L | 70–74 OT | Regular | Hilton Coliseum |
| 75 | 2018-01-06 | 2017–18 | Iowa State | Oklahoma State | B12 | Away | L | 87–96 OT | Regular | Gallagher-Iba Arena |
| 76 | 2018-01-09 | 2017–18 | Iowa State | #12 Kansas | B12 | Away | L | 78–83 | Regular | Allen Fieldhouse |
| 77 | 2018-01-13 | 2017–18 | Iowa State | Baylor | B12 | Home | W | 75–65 | Regular | Hilton Coliseum |
| 78 | 2018-01-17 | 2017–18 | Iowa State | #24 TCU | B12 | Away | L | 73–96 | Regular | Schollmaier Arena |
| 79 | 2018-01-20 | 2017–18 | Iowa State | #8 Texas Tech | B12 | Home | W | 70–52 | Regular | Hilton Coliseum |
| 80 | 2018-01-22 | 2017–18 | Iowa State | Texas | B12 | Away | L | 57–73 | Regular | Frank Erwin Center |
| 81 | 2018-01-27 | 2017–18 | Iowa State | #22 Tennessee | SEC | Home | L | 45–68 | Regular | Hilton Coliseum |
| 82 | 2018-01-31 | 2017–18 | Iowa State | #15 West Virginia | B12 | Home | W | 93–77 | Regular | Hilton Coliseum |
| 83 | 2018-02-03 | 2017–18 | Iowa State | Baylor | B12 | Away | L | 67–81 | Regular | Ferrell Center |
| 84 | 2018-02-07 | 2017–18 | Iowa State | #7 Texas Tech | B12 | Away | L | 58–76 | Regular | United Supermarkets Arena |
| 85 | 2018-02-10 | 2017–18 | Iowa State | #17 Oklahoma | B12 | Home | W | 88–80 | Regular | Hilton Coliseum |
| 86 | 2018-02-13 | 2017–18 | Iowa State | #13 Kansas | B12 | Home | L | 77–83 | Regular | Hilton Coliseum |
| 87 | 2018-02-17 | 2017–18 | Iowa State | Kansas State | B12 | Away | L | 66–78 | Regular | Bramlage Coliseum |
| 88 | 2018-02-21 | 2017–18 | Iowa State | TCU | B12 | Home | L | 83–89 | Regular | Hilton Coliseum |
| 89 | 2018-02-24 | 2017–18 | Iowa State | #21 West Virginia | B12 | Away | L | 70–85 | Regular | Hope Coliseum |
| 90 | 2018-02-27 | 2017–18 | Iowa State | Oklahoma State | B12 | Home | L | 71–80 | Regular | Hilton Coliseum |
| 91 | 2018-03-02 | 2017–18 | Iowa State | Oklahoma | B12 | Away | L | 60–81 | Regular | Lloyd Noble Center |
| 92 | 2018-11-06 | 2018–19 | Iowa State | Alabama State | SWAC | Home | W | 79–53 | Regular | Hilton Coliseum |
| 93 | 2018-11-09 | 2018–19 | Iowa State | Missouri | SEC | Home | W | 76–59 | Regular | Hilton Coliseum |
| 94 | 2018-11-12 | 2018–19 | Iowa State | Texas Southern | SWAC | Home | W | 85–73 | Regular | Hilton Coliseum |
| 95 | 2018-11-19 | 2018–19 | Iowa State | Arizona Wildcats | Pacific 12 | Neutral | L | 66–71 | Regular | Lahaina Civic Center |
| 96 | 2018-11-20 | 2018–19 | Iowa State | Illinois | B10 | Neutral | W | 84–68 | Regular | Lahaina Civic Center |
| 97 | 2018-11-21 | 2018–19 | Iowa State | San Diego State | Mountain West | Neutral | W | 87–57 | Regular | Lahaina Civic Center |
| 98 | 2018-11-26 | 2018–19 | Iowa State | Omaha | Summit | Home | W | 82–55 | Regular | Hilton Coliseum |
| 99 | 2018-12-03 | 2018–19 | Iowa State | North Dakota State | Summit | Home | W | 81–59 | Regular | Hilton Coliseum |
| 100 | 2018-12-06 | 2018–19 | Iowa State | #18 Iowa | B10 | Away | L | 84–98 | Regular | Carver-Hawkeye Arena |
| 101 | 2018-12-09 | 2018–19 | Iowa State | Southern | SWAC | Home | W | 101–65 | Regular | Hilton Coliseum |
| 102 | 2018-12-15 | 2018–19 | Iowa State | Drake | Missouri Valley | Neutral | W | 77–68 | Regular | Wells Fargo Arena |
| 103 | 2018-12-21 | 2018–19 | Iowa State | Eastern Illinois | OVC | Home | W | 101–53 | Regular | Hilton Coliseum |
| 104 | 2019-01-02 | 2018–19 | Iowa State | Oklahoma State | B12 | Away | W | 69–63 | Regular | Gallagher-Iba Arena |
| 105 | 2019-01-05 | 2018–19 | Iowa State | #5 Kansas | B12 | Home | W | 77–60 | Regular | Hilton Coliseum |
| 106 | 2019-01-08 | 2018–19 | #20 Iowa State | Baylor | B12 | Away | L | 70–73 | Regular | Ferrell Center |
| 107 | 2019-01-12 | 2018–19 | #20 Iowa State | Kansas State | B12 | Home | L | 57–58 | Regular | Hilton Coliseum |
| 108 | 2019-01-16 | 2018–19 | #20 Iowa State | #8 Texas Tech | B12 | Away | W | 68–64 | Regular | United Supermarkets Arena |
| 109 | 2019-01-19 | 2018–19 | #20 Iowa State | Oklahoma State | B12 | Home | W | 72–59 | Regular | Hilton Coliseum |
| 110 | 2019-01-21 | 2018–19 | #24 Iowa State | #9 Kansas | B12 | Away | L | 76–80 | Regular | Allen Fieldhouse |
| 111 | 2019-01-26 | 2018–19 | #24 Iowa State | #20 Mississippi | SEC | Away | W | 87–73 | Regular | The Sandy and John Black Pavilion at Ole Miss |
| 112 | 2019-01-30 | 2018–19 | #20 Iowa State | West Virginia | B12 | Home | W | 93–68 | Regular | Hilton Coliseum |
| 113 | 2019-02-02 | 2018–19 | #20 Iowa State | Texas | B12 | Home | W | 65–60 | Regular | Hilton Coliseum |
| 114 | 2019-02-04 | 2018–19 | #17 Iowa State | Oklahoma | B12 | Away | W | 75–74 | Regular | Lloyd Noble Center |
| 115 | 2019-02-09 | 2018–19 | #17 Iowa State | TCU | B12 | Home | L | 83–92 | Regular | Hilton Coliseum |
| 116 | 2019-02-16 | 2018–19 | #23 Iowa State | #18 Kansas State | B12 | Away | W | 78–64 | Regular | Bramlage Coliseum |
| 117 | 2019-02-19 | 2018–19 | #19 Iowa State | Baylor | B12 | Home | L | 69–73 | Regular | Hilton Coliseum |
| 118 | 2019-02-23 | 2018–19 | #19 Iowa State | TCU | B12 | Away | L | 72–75 | Regular | Schollmaier Arena |
| 119 | 2019-02-25 | 2018–19 | #19 Iowa State | Oklahoma | B12 | Home | W | 78–61 | Regular | Hilton Coliseum |
| 120 | 2019-03-02 | 2018–19 | #19 Iowa State | Texas | B12 | Away | L | 69–86 | Regular | Frank Erwin Center |
| 121 | 2019-03-06 | 2018–19 | #19 Iowa State | West Virginia | B12 | Away | L | 75–90 | Regular | Hope Coliseum |
| 122 | 2019-03-09 | 2018–19 | #19 Iowa State | #8 Texas Tech | B12 | Home | L | 73–80 | Regular | Hilton Coliseum |
| 123 | 2019-11-05 | 2019–20 | Iowa State | Mississippi Valley State | SWAC | Home | W | 110–74 | Regular | Hilton Coliseum |
| 124 | 2019-11-09 | 2019–20 | Iowa State | Oregon State | Pacific 12 | Away | L | 74–80 | Regular | Gill Coliseum |
| 125 | 2019-11-12 | 2019–20 | Iowa State | Northern Illinois | MAC | Home | W | 70–52 | Regular | Hilton Coliseum |
| 126 | 2019-11-19 | 2019–20 | Iowa State | Southern Mississippi | CUSA | Home | W | 73–45 | Regular | Hilton Coliseum |
| 127 | 2019-11-27 | 2019–20 | Iowa State | Michigan | B10 | Neutral | L | 76–83 | Regular | Imperial Arena |
| 128 | 2019-11-28 | 2019–20 | Iowa State | Alabama | SEC | Neutral | W | 104–89 | Regular | Imperial Arena |
| 129 | 2019-11-29 | 2019–20 | Iowa State | #13 Seton Hall | Big East | Neutral | L | 76–84 | Regular | Imperial Arena |
| 130 | 2019-12-04 | 2019–20 | Iowa State | Kansas City | WAC | Home | W | 79–61 | Regular | Hilton Coliseum |
| 131 | 2019-12-08 | 2019–20 | Iowa State | #16 Seton Hall | Big East | Home | W | 76–66 | Regular | Hilton Coliseum |
| 132 | 2019-12-12 | 2019–20 | Iowa State | Iowa | B10 | Home | L | 68–84 | Regular | Hilton Coliseum |
| 133 | 2019-12-22 | 2019–20 | Iowa State | Purdue Fort Wayne | Summit | Home | W | 89–59 | Regular | Hilton Coliseum |
| 134 | 2019-12-31 | 2019–20 | Iowa State | Florida A&M | MEAC | Home | L | 68–70 | Regular | Hilton Coliseum |
| 135 | 2020-01-04 | 2019–20 | Iowa State | TCU | B12 | Away | L | 79–81 OT | Regular | Schollmaier Arena |
| 136 | 2020-01-08 | 2019–20 | Iowa State | #3 Kansas | B12 | Home | L | 53–79 | Regular | Hilton Coliseum |
| 137 | 2020-01-11 | 2019–20 | Iowa State | Oklahoma | B12 | Home | W | 81–68 | Regular | Hilton Coliseum |
| 138 | 2020-01-15 | 2019–20 | Iowa State | #2 Baylor | B12 | Away | L | 55–68 | Regular | Ferrell Center |
| 139 | 2020-01-18 | 2019–20 | Iowa State | #23 Texas Tech | B12 | Away | L | 52–72 | Regular | United Supermarkets Arena |
| 140 | 2020-01-21 | 2019–20 | Iowa State | Oklahoma State | B12 | Home | W | 89–82 | Regular | Hilton Coliseum |
| 141 | 2020-01-25 | 2019–20 | Iowa State | #16 Auburn | SEC | Away | L | 76–80 | Regular | Neville Arena |
| 142 | 2020-01-29 | 2019–20 | Iowa State | #1 Baylor | B12 | Home | L | 53–67 | Regular | Hilton Coliseum |
| 143 | 2020-02-01 | 2019–20 | Iowa State | Texas | B12 | Away | L | 68–72 | Regular | Frank Erwin Center |
| 144 | 2020-02-05 | 2019–20 | Iowa State | #13 West Virginia | B12 | Away | L | 61–76 | Regular | Hope Coliseum |
| 145 | 2020-02-08 | 2019–20 | Iowa State | Kansas State | B12 | Home | W | 73–63 | Regular | Hilton Coliseum |
| 146 | 2020-02-12 | 2019–20 | Iowa State | Oklahoma | B12 | Away | L | 61–90 | Regular | Lloyd Noble Center |
| 147 | 2020-02-15 | 2019–20 | Iowa State | Texas | B12 | Home | W | 81–52 | Regular | Hilton Coliseum |
| 148 | 2020-02-17 | 2019–20 | Iowa State | #3 Kansas | B12 | Away | L | 71–91 | Regular | Allen Fieldhouse |
| 149 | 2020-02-22 | 2019–20 | Iowa State | Texas Tech | B12 | Home | L | 57–87 | Regular | Hilton Coliseum |
| 150 | 2020-02-25 | 2019–20 | Iowa State | TCU | B12 | Home | W | 65–59 | Regular | Hilton Coliseum |
| 151 | 2020-02-29 | 2019–20 | Iowa State | Oklahoma State | B12 | Away | L | 61–73 | Regular | Gallagher-Iba Arena |
| 152 | 2020-03-03 | 2019–20 | Iowa State | West Virginia | B12 | Home | L | 71–77 | Regular | Hilton Coliseum |
| 153 | 2020-03-07 | 2019–20 | Iowa State | Kansas State | B12 | Away | L | 63–79 | Regular | Bramlage Coliseum |
| 154 | 2020-11-29 | 2020–21 | Iowa State | Arkansas-Pine Bluff | SWAC | Home | W | 80–63 | Regular | Hilton Coliseum |
| 155 | 2020-12-02 | 2020–21 | Iowa State | South Dakota State | Summit | Home | L | 68–71 | Regular | Hilton Coliseum |
| 156 | 2020-12-11 | 2020–21 | Iowa State | #3 Iowa | B10 | Away | L | 77–105 | Regular | Carver-Hawkeye Arena |
| 157 | 2020-12-15 | 2020–21 | Iowa State | Kansas State | B12 | Home | L | 65–74 | Regular | Hilton Coliseum |
| 158 | 2020-12-18 | 2020–21 | Iowa State | #8 West Virginia | B12 | Away | L | 65–70 | Regular | Hope Coliseum |
| 159 | 2020-12-20 | 2020–21 | Iowa State | Jackson State | SWAC | Home | W | 60–45 | Regular | Hilton Coliseum |
| 160 | 2021-01-02 | 2020–21 | Iowa State | #2 Baylor | B12 | Home | L | 65–76 | Regular | Hilton Coliseum |
| 161 | 2021-01-05 | 2020–21 | Iowa State | #4 Texas | B12 | Away | L | 72–78 | Regular | Frank Erwin Center |
| 162 | 2021-01-09 | 2020–21 | Iowa State | #18 Texas Tech | B12 | Home | L | 64–91 | Regular | Hilton Coliseum |
| 163 | 2021-01-25 | 2020–21 | Iowa State | Oklahoma State | B12 | Home | L | 60–81 | Regular | Hilton Coliseum |
| 164 | 2021-01-30 | 2020–21 | Iowa State | Mississippi State | SEC | Away | L | 56–95 | Regular | Humphrey Coliseum |
| 165 | 2021-02-02 | 2020–21 | Iowa State | #17 West Virginia | B12 | Home | L | 72–76 | Regular | Hilton Coliseum |
| 166 | 2021-02-06 | 2020–21 | Iowa State | #9 Oklahoma | B12 | Away | L | 72–79 | Regular | Lloyd Noble Center |
| 167 | 2021-02-09 | 2020–21 | Iowa State | TCU | B12 | Away | L | 76–79 | Regular | Schollmaier Arena |
| 168 | 2021-02-11 | 2020–21 | Iowa State | Kansas | B12 | Away | L | 64–97 | Regular | Allen Fieldhouse |
| 169 | 2021-02-13 | 2020–21 | Iowa State | Kansas | B12 | Home | L | 50–64 | Regular | Hilton Coliseum |
| 170 | 2021-02-16 | 2020–21 | Iowa State | Oklahoma State | B12 | Away | L | 58–76 | Regular | Gallagher-Iba Arena |
| 171 | 2021-02-20 | 2020–21 | Iowa State | #9 Oklahoma | B12 | Home | L | 56–66 | Regular | Hilton Coliseum |
| 172 | 2021-02-23 | 2020–21 | Iowa State | #2 Baylor | B12 | Away | L | 72–77 | Regular | Ferrell Center |
| 173 | 2021-02-27 | 2020–21 | Iowa State | TCU | B12 | Home | L | 72–76 | Regular | Hilton Coliseum |
| 174 | 2021-03-02 | 2020–21 | Iowa State | #15 Texas | B12 | Home | L | 67–81 | Regular | Hilton Coliseum |
| 175 | 2021-03-04 | 2020–21 | Iowa State | #18 Texas Tech | B12 | Away | L | 54–81 | Regular | United Supermarkets Arena |
| 176 | 2021-03-06 | 2020–21 | Iowa State | Kansas State | B12 | Away | L | 56–61 | Regular | Bramlage Coliseum |